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ICD↔CPT crosswalk

CPT J1599: ICD-10 codes that support medical necessity

1433 covered diagnosis codes under Medicare coverage policies (LCD/NCD)

These ICD-10-CM diagnoses support medical necessity for CPT J1599 under Medicare coverage policies (LCDs, NCDs, and Billing & Coding articles). Billing CPT J1599 with a diagnosis that isn't covered typically denies as CARC 50 — not medically necessary.

National approximation. Coverage varies by MAC and state — confirm against the specific LCD/NCD and article that applies to your jurisdiction and date of service.

ICD-10Description
A41.01Sepsis due to Methicillin susceptible Staphylococcus aureus
A41.02Sepsis due to Methicillin resistant Staphylococcus aureus
A41.1Sepsis due to other specified staphylococcus
A41.2Sepsis due to unspecified staphylococcus
A41.3Sepsis due to Hemophilus influenzae
A41.4Sepsis due to anaerobes
A41.50Gram-negative sepsis, unspecified
A41.51Sepsis due to Escherichia coli [E. coli]
A41.52Sepsis due to Pseudomonas
A41.53Sepsis due to Serratia
A41.59Other Gram-negative sepsis
A41.81Sepsis due to Enterococcus
A41.89Other specified sepsis
A41.9Sepsis, unspecified organism
A42.7Actinomycotic sepsis
A48.3Toxic shock syndrome
A54.86Gonococcal sepsis
A85.8Other specified viral encephalitis
A92.31West Nile virus infection with encephalitis
A92.39West Nile virus infection with other complications
B08.3Erythema infectiosum [fifth disease]
B16.1Acute hepatitis B with delta-agent without hepatic coma
B16.2Acute hepatitis B without delta-agent with hepatic coma
B16.9Acute hepatitis B without delta-agent and without hepatic coma
B17.0Acute delta-(super) infection of hepatitis B carrier
B18.0Chronic viral hepatitis B with delta-agent
B18.1Chronic viral hepatitis B without delta-agent
B19.10Unspecified viral hepatitis B without hepatic coma
B19.11Unspecified viral hepatitis B with hepatic coma
B20Human immunodeficiency virus [HIV] disease
B25.0Cytomegaloviral pneumonitis
B25.1Cytomegaloviral hepatitis
B25.2Cytomegaloviral pancreatitis
B25.8Other cytomegaloviral diseases
B25.9Cytomegaloviral disease, unspecified
B34.3Parvovirus infection, unspecified
B37.7Candidal sepsis
B97.4Respiratory syncytial virus as the cause of diseases classified elsewhere
C88.00Waldenstrom macroglobulinemia not having achieved remission
C88.20Heavy chain disease not having achieved remission
C88.21Heavy chain disease, in remission
C88.30Immunoproliferative small intestinal disease not having achieved remission
C88.31Immunoproliferative small intestinal disease, in remission
C88.40Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma] not having achieved remission
C88.41Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma], in remission
C88.80Other malignant immunoproliferative diseases not having achieved remission
C88.81Other malignant immunoproliferative diseases, in remission
C88.90Malignant immunoproliferative disease, unspecified not having achieved remission
C88.91Malignant immunoproliferative disease, unspecified, in remission
C90.00Multiple myeloma not having achieved remission
C90.01Multiple myeloma in remission
C90.02Multiple myeloma in relapse
C90.10Plasma cell leukemia not having achieved remission
C90.11Plasma cell leukemia in remission
C90.12Plasma cell leukemia in relapse
C90.20Extramedullary plasmacytoma not having achieved remission
C90.21Extramedullary plasmacytoma in remission
C90.22Extramedullary plasmacytoma in relapse
C90.30Solitary plasmacytoma not having achieved remission
C90.31Solitary plasmacytoma in remission
C90.32Solitary plasmacytoma in relapse
C91.10Chronic lymphocytic leukemia of B-cell type not having achieved remission
C91.11Chronic lymphocytic leukemia of B-cell type in remission
C91.12Chronic lymphocytic leukemia of B-cell type in relapse
C91.Z0Other lymphoid leukemia not having achieved remission
C91.Z2Other lymphoid leukemia, in relapse
D47.3Essential (hemorrhagic) thrombocythemia
D55.0Anemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency
D55.1Anemia due to other disorders of glutathione metabolism
D55.21Anemia due to pyruvate kinase deficiency
D55.29Anemia due to other disorders of glycolytic enzymes
D55.3Anemia due to disorders of nucleotide metabolism
D55.8Other anemias due to enzyme disorders
D55.9Anemia due to enzyme disorder, unspecified
D56.0Alpha thalassemia
D56.1Beta thalassemia
D56.2Delta-beta thalassemia
D56.3Thalassemia minor
D56.4Hereditary persistence of fetal hemoglobin [HPFH]
D56.5Hemoglobin E-beta thalassemia
D56.8Other thalassemias
D56.9Thalassemia, unspecified
D57.00Hb-SS disease with crisis, unspecified
D57.01Hb-SS disease with acute chest syndrome
D57.02Hb-SS disease with splenic sequestration
D57.03Hb-SS disease with cerebral vascular involvement
D57.04Hb-SS disease with dactylitis
D57.09Hb-SS disease with crisis with other specified complication
D57.1Sickle-cell disease without crisis
D57.20Sickle-cell/Hb-C disease without crisis
D57.211Sickle-cell/Hb-C disease with acute chest syndrome
D57.212Sickle-cell/Hb-C disease with splenic sequestration
D57.213Sickle-cell/Hb-C disease with cerebral vascular involvement
D57.214Sickle-cell/Hb-C disease with dactylitis
D57.218Sickle-cell/Hb-C disease with crisis with other specified complication
D57.219Sickle-cell/Hb-C disease with crisis, unspecified
D57.3Sickle-cell trait
D57.414Sickle-cell thalassemia, unspecified, with dactylitis
D57.434Sickle-cell thalassemia beta zero with dactylitis
D57.454Sickle-cell thalassemia beta plus with dactylitis
D57.80Other sickle-cell disorders without crisis
D57.811Other sickle-cell disorders with acute chest syndrome
D57.812Other sickle-cell disorders with splenic sequestration
D57.813Other sickle-cell disorders with cerebral vascular involvement
D57.814Other sickle-cell disorders with dactylitis
D57.818Other sickle-cell disorders with crisis with other specified complication
D57.819Other sickle-cell disorders with crisis, unspecified
D58.0Hereditary spherocytosis
D58.1Hereditary elliptocytosis
D58.2Other hemoglobinopathies
D58.8Other specified hereditary hemolytic anemias
D58.9Hereditary hemolytic anemia, unspecified
D59.0Drug-induced autoimmune hemolytic anemia
D59.10Autoimmune hemolytic anemia, unspecified
D59.11Warm autoimmune hemolytic anemia
D59.12Cold autoimmune hemolytic anemia
D59.13Mixed type autoimmune hemolytic anemia
D59.19Other autoimmune hemolytic anemia
D59.2Drug-induced nonautoimmune hemolytic anemia
D59.4Other nonautoimmune hemolytic anemias
D59.9Acquired hemolytic anemia, unspecified
D60.0Chronic acquired pure red cell aplasia
D60.1Transient acquired pure red cell aplasia
D60.8Other acquired pure red cell aplasias
D60.9Acquired pure red cell aplasia, unspecified
D61.01Constitutional (pure) red blood cell aplasia
D61.02Shwachman-Diamond syndrome
D61.1Drug-induced aplastic anemia
D61.2Aplastic anemia due to other external agents
D61.3Idiopathic aplastic anemia
D61.810Antineoplastic chemotherapy induced pancytopenia
D61.811Other drug-induced pancytopenia
D61.818Other pancytopenia
D61.89Other specified aplastic anemias and other bone marrow failure syndromes
D68.01Von Willebrand disease, type 1
D68.020Von Willebrand disease, type 2A
D68.021Von Willebrand disease, type 2B
D68.022Von Willebrand disease, type 2M
D68.023Von Willebrand disease, type 2N
D68.03Von Willebrand disease, type 3
D68.04Acquired von Willebrand disease
D68.09Other von Willebrand disease
D69.0Allergic purpura
D69.3Immune thrombocytopenic purpura
D69.41Evans syndrome
D69.42Congenital and hereditary thrombocytopenia purpura
D69.49Other primary thrombocytopenia
D69.51Posttransfusion purpura
D69.59Other secondary thrombocytopenia
D70.8Other neutropenia
D70.9Neutropenia, unspecified
D80.0Hereditary hypogammaglobulinemia
D80.1Nonfamilial hypogammaglobulinemia
D80.2Selective deficiency of immunoglobulin A [IgA]
D80.3Selective deficiency of immunoglobulin G [IgG] subclasses
D80.4Selective deficiency of immunoglobulin M [IgM]
D80.5Immunodeficiency with increased immunoglobulin M [IgM]
D80.6Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinemia
D80.7Transient hypogammaglobulinemia of infancy
D80.8Other immunodeficiencies with predominantly antibody defects
D80.9Immunodeficiency with predominantly antibody defects, unspecified
D81.0Severe combined immunodeficiency [SCID] with reticular dysgenesis
D81.1Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
D81.2Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
D81.4Nezelof's syndrome
D81.5Purine nucleoside phosphorylase [PNP] deficiency
D81.6Major histocompatibility complex class I deficiency
D81.7Major histocompatibility complex class II deficiency
D81.82Activated Phosphoinositide 3-kinase Delta Syndrome [APDS]
D81.89Other combined immunodeficiencies
D81.9Combined immunodeficiency, unspecified
D82.0Wiskott-Aldrich syndrome
D82.1Di George's syndrome
D82.2Immunodeficiency with short-limbed stature
D82.3Immunodeficiency following hereditary defective response to Epstein-Barr virus
D82.4Hyperimmunoglobulin E [IgE] syndrome
D82.8Immunodeficiency associated with other specified major defects
D82.9Immunodeficiency associated with major defect, unspecified
D83.0Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
D83.1Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
D83.2Common variable immunodeficiency with autoantibodies to B- or T-cells
D83.8Other common variable immunodeficiencies
D83.9Common variable immunodeficiency, unspecified
D84.0Lymphocyte function antigen-1 [LFA-1] defect
D84.1Defects in the complement system
D84.9Immunodeficiency, unspecified
D89.3Immune reconstitution syndrome
D89.810Acute graft-versus-host disease
D89.811Chronic graft-versus-host disease
D89.812Acute on chronic graft-versus-host disease
D89.813Graft-versus-host disease, unspecified
D89.82Autoimmune lymphoproliferative syndrome [ALPS]
D89.831Cytokine release syndrome, grade 1
D89.832Cytokine release syndrome, grade 2
D89.833Cytokine release syndrome, grade 3
D89.834Cytokine release syndrome, grade 4
D89.835Cytokine release syndrome, grade 5
D89.839Cytokine release syndrome, grade unspecified
D89.84IgG4-related disease
D89.89Other specified disorders involving the immune mechanism, not elsewhere classified
D89.9Disorder involving the immune mechanism, unspecified
G04.81Other encephalitis and encephalomyelitis
G11.3Cerebellar ataxia with defective DNA repair
G13.0Paraneoplastic neuromyopathy and neuropathy
G13.1Other systemic atrophy primarily affecting central nervous system in neoplastic disease
G25.82Stiff-man syndrome
G35.ARelapsing-remitting multiple sclerosis
G35.B0Primary progressive multiple sclerosis, unspecified
G35.B1Active primary progressive multiple sclerosis
G35.B2Non-active primary progressive multiple sclerosis
G35.C0Secondary progressive multiple sclerosis, unspecified
G35.C1Active secondary progressive multiple sclerosis
G35.C2Non-active secondary progressive multiple sclerosis
G40.301Generalized idiopathic epilepsy and epileptic syndromes, not intractable, with status epilepticus
G40.311Generalized idiopathic epilepsy and epileptic syndromes, intractable, with status epilepticus
G40.319Generalized idiopathic epilepsy and epileptic syndromes, intractable, without status epilepticus
G40.411Other generalized epilepsy and epileptic syndromes, intractable, with status epilepticus
G40.419Other generalized epilepsy and epileptic syndromes, intractable, without status epilepticus
G57.81Other specified mononeuropathies of right lower limb
G57.82Other specified mononeuropathies of left lower limb
G57.83Other specified mononeuropathies of bilateral lower limbs
G60.0Hereditary motor and sensory neuropathy
G60.1Refsum's disease
G60.2Neuropathy in association with hereditary ataxia
G60.3Idiopathic progressive neuropathy
G60.8Other hereditary and idiopathic neuropathies
G61.0Guillain-Barre syndrome
G61.1Serum neuropathy
G61.81Chronic inflammatory demyelinating polyneuritis
G61.82Multifocal motor neuropathy
G61.89Other inflammatory polyneuropathies
G62.0Drug-induced polyneuropathy
G62.81Critical illness polyneuropathy
G62.89Other specified polyneuropathies
G64Other disorders of peripheral nervous system
G65.0Sequelae of Guillain-Barre syndrome
G70.00Myasthenia gravis without (acute) exacerbation
G70.01Myasthenia gravis with (acute) exacerbation
G70.80Lambert-Eaton syndrome, unspecified
G70.81Lambert-Eaton syndrome in disease classified elsewhere
G70.9Myoneural disorder, unspecified
G72.41Inclusion body myositis [IBM]
G72.49Other inflammatory and immune myopathies, not elsewhere classified
G72.81Critical illness myopathy
G72.89Other specified myopathies
G73.1Lambert-Eaton syndrome in neoplastic disease
G73.3Myasthenic syndromes in other diseases classified elsewhere
G93.45Developmental and epileptic encephalopathy
G93.49Other encephalopathy
H20.011Primary iridocyclitis, right eye
H20.012Primary iridocyclitis, left eye
H20.013Primary iridocyclitis, bilateral
H20.021Recurrent acute iridocyclitis, right eye
H20.022Recurrent acute iridocyclitis, left eye
H20.023Recurrent acute iridocyclitis, bilateral
H20.031Secondary infectious iridocyclitis, right eye
H20.032Secondary infectious iridocyclitis, left eye
H20.033Secondary infectious iridocyclitis, bilateral
H20.041Secondary noninfectious iridocyclitis, right eye
H20.042Secondary noninfectious iridocyclitis, left eye
H20.043Secondary noninfectious iridocyclitis, bilateral
H20.051Hypopyon, right eye
H20.052Hypopyon, left eye
H20.053Hypopyon, bilateral
H20.11Chronic iridocyclitis, right eye
H20.12Chronic iridocyclitis, left eye
H20.13Chronic iridocyclitis, bilateral
H20.21Lens-induced iridocyclitis, right eye
H20.22Lens-induced iridocyclitis, left eye
H20.23Lens-induced iridocyclitis, bilateral
H20.811Fuchs' heterochromic cyclitis, right eye
H20.812Fuchs' heterochromic cyclitis, left eye
H20.813Fuchs' heterochromic cyclitis, bilateral
H20.821Vogt-Koyanagi syndrome, right eye
H20.822Vogt-Koyanagi syndrome, left eye
H20.823Vogt-Koyanagi syndrome, bilateral
H35.89Other specified retinal disorders
H46.8Other optic neuritis
H54.7Unspecified visual loss
I30.8Other forms of acute pericarditis
I40.8Other acute myocarditis
I44.0Atrioventricular block, first degree
I44.1Atrioventricular block, second degree
I44.2Atrioventricular block, complete
I44.39Other atrioventricular block
I45.0Right fascicular block
I45.19Other right bundle-branch block
I45.2Bifascicular block
I45.3Trifascicular block
I45.4Nonspecific intraventricular block
I45.5Other specified heart block
I45.6Pre-excitation syndrome
I45.81Long QT syndrome
I45.89Other specified conduction disorders
I47.0Re-entry ventricular arrhythmia
I47.21Torsades de pointes
I47.29Other ventricular tachycardia
I78.8Other diseases of capillaries
J20.5Acute bronchitis due to respiratory syncytial virus
L10.0Pemphigus vulgaris
L10.1Pemphigus vegetans
L10.2Pemphigus foliaceous
L10.3Brazilian pemphigus [fogo selvagem]
L10.4Pemphigus erythematosus
L10.5Drug-induced pemphigus
L10.81Paraneoplastic pemphigus
L10.89Other pemphigus
L10.9Pemphigus, unspecified
L12.0Bullous pemphigoid
L12.1Cicatricial pemphigoid
L12.30Acquired epidermolysis bullosa, unspecified
L12.31Epidermolysis bullosa due to drug
L12.35Other acquired epidermolysis bullosa
L12.8Other pemphigoid
L12.9Pemphigoid, unspecified
L13.8Other specified bullous disorders
L14Bullous disorders in diseases classified elsewhere
L51.1Stevens-Johnson syndrome
L51.2Toxic epidermal necrolysis [Lyell]
L51.3Stevens-Johnson syndrome-toxic epidermal necrolysis overlap syndrome
L88Pyoderma gangrenosum
L90.1Anetoderma of Schweninger-Buzzi
L90.2Anetoderma of Jadassohn-Pellizzari
L90.6Striae atrophicae
L95.0Livedoid vasculitis
L95.9Vasculitis limited to the skin, unspecified
L98.5Mucinosis of the skin
M06.4Inflammatory polyarthropathy
M30.0Polyarteritis nodosa
M30.1Polyarteritis with lung involvement [Churg-Strauss]
M30.2Juvenile polyarteritis
M30.3Mucocutaneous lymph node syndrome [Kawasaki]
M31.10Thrombotic microangiopathy, unspecified
M31.19Other thrombotic microangiopathy
M31.30Wegener's granulomatosis without renal involvement
M31.31Wegener's granulomatosis with renal involvement
M31.7Microscopic polyangiitis
M32.0Drug-induced systemic lupus erythematosus
M32.10Systemic lupus erythematosus, organ or system involvement unspecified
M32.11Endocarditis in systemic lupus erythematosus
M32.12Pericarditis in systemic lupus erythematosus
M32.13Lung involvement in systemic lupus erythematosus
M32.14Glomerular disease in systemic lupus erythematosus
M32.15Tubulo-interstitial nephropathy in systemic lupus erythematosus
M32.19Other organ or system involvement in systemic lupus erythematosus
M32.8Other forms of systemic lupus erythematosus
M32.9Systemic lupus erythematosus, unspecified
M33.00Juvenile dermatomyositis, organ involvement unspecified
M33.01Juvenile dermatomyositis with respiratory involvement
M33.02Juvenile dermatomyositis with myopathy
M33.03Juvenile dermatomyositis without myopathy
M33.09Juvenile dermatomyositis with other organ involvement
M33.10Other dermatomyositis, organ involvement unspecified
M33.11Other dermatomyositis with respiratory involvement
M33.12Other dermatomyositis with myopathy
M33.13Other dermatomyositis without myopathy
M33.19Other dermatomyositis with other organ involvement
M33.20Polymyositis, organ involvement unspecified
M33.21Polymyositis with respiratory involvement
M33.22Polymyositis with myopathy
M33.29Polymyositis with other organ involvement
M33.90Dermatopolymyositis, unspecified, organ involvement unspecified
M33.91Dermatopolymyositis, unspecified with respiratory involvement
M33.92Dermatopolymyositis, unspecified with myopathy
M33.93Dermatopolymyositis, unspecified without myopathy
M33.99Dermatopolymyositis, unspecified with other organ involvement
M34.83Systemic sclerosis with polyneuropathy
M35.5Multifocal fibrosclerosis
M35.81Multisystem inflammatory syndrome
M35.89Other specified systemic involvement of connective tissue
M36.0Dermato(poly)myositis in neoplastic disease
M60.80Other myositis, unspecified site
M60.9Myositis, unspecified
N02.8Recurrent and persistent hematuria with other morphologic changes
N28.9Disorder of kidney and ureter, unspecified
O09.891Supervision of other high risk pregnancies, first trimester
O09.892Supervision of other high risk pregnancies, second trimester
O09.893Supervision of other high risk pregnancies, third trimester
O09.899Supervision of other high risk pregnancies, unspecified trimester
P61.0Transient neonatal thrombocytopenia
R65.20Severe sepsis without septic shock
R65.21Severe sepsis with septic shock
R78.81Bacteremia
S01.00XAUnspecified open wound of scalp, initial encounter
S01.01XALaceration without foreign body of scalp, initial encounter
S01.02XALaceration with foreign body of scalp, initial encounter
S01.03XAPuncture wound without foreign body of scalp, initial encounter
S01.04XAPuncture wound with foreign body of scalp, initial encounter
S01.101AUnspecified open wound of right eyelid and periocular area, initial encounter
S01.102AUnspecified open wound of left eyelid and periocular area, initial encounter
S01.111ALaceration without foreign body of right eyelid and periocular area, initial encounter
S01.112ALaceration without foreign body of left eyelid and periocular area, initial encounter
S01.121ALaceration with foreign body of right eyelid and periocular area, initial encounter
S01.122ALaceration with foreign body of left eyelid and periocular area, initial encounter
S01.131APuncture wound without foreign body of right eyelid and periocular area, initial encounter
S01.132APuncture wound without foreign body of left eyelid and periocular area, initial encounter
S01.141APuncture wound with foreign body of right eyelid and periocular area, initial encounter
S01.142APuncture wound with foreign body of left eyelid and periocular area, initial encounter
S01.151AOpen bite of right eyelid and periocular area, initial encounter
S01.152AOpen bite of left eyelid and periocular area, initial encounter

Showing the first 400 of 1433 covered codes — this procedure has a large covered-diagnosis set; see the governing LCD/article for the complete list.

Frequently asked questions

Which ICD-10 codes support medical necessity for CPT J1599?

Medicare coverage policies (LCDs/NCDs and Billing & Coding articles) list 1433 ICD-10 diagnosis codes that support medical necessity for CPT J1599. The covered codes are listed on this page. Coverage varies by MAC/state — always confirm against the policy that applies to you.

What is a medical-necessity (LCD/NCD) crosswalk?

A claim whose procedure isn't supported by a covered diagnosis denies as "not medically necessary" (CARC 50). CMS coverage policies define which diagnoses justify a procedure; this page is the ICD-10 → CPT J1599 view of that relationship.

Catch medical-necessity denials before you bill. CareNiva scrubs claims against LCD/NCD coverage and flags unsupported diagnoses — in the same platform you run visits and billing.

More free billing tools: all crosswalks · NCCI edits · Medicare fees · denial codes

Informational only, not coding, billing, or legal advice. Based on CMS Medicare Coverage Database data; verify the current LCD/NCD for your MAC before billing.

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