D57: Sickle-cell disorders

Codes under D57 (Sickle-cell disorders). A ✓ marks a billable (fully specified) code; category codes without a ✓ are not billable on their own.

Code	Description	Billable
D57.0	Hb-SS disease with crisis	—
D57.00	Hb-SS disease with crisis, unspecified	✓
D57.01	Hb-SS disease with acute chest syndrome	✓
D57.1	Sickle-cell disease without crisis	✓
D57.02	Hb-SS disease with splenic sequestration	✓
D57.2	Sickle-cell/Hb-C disease	—
D57.03	Hb-SS disease with cerebral vascular involvement	✓
D57.3	Sickle-cell trait	✓
D57.04	Hb-SS disease with dactylitis	✓
D57.4	Sickle-cell thalassemia	—
D57.8	Other sickle-cell disorders	—
D57.09	Hb-SS disease with crisis with other specified complication	✓
D57.20	Sickle-cell/Hb-C disease without crisis	✓
D57.21	Sickle-cell/Hb-C disease with crisis	—
D57.40	Sickle-cell thalassemia without crisis	✓
D57.41	Sickle-cell thalassemia, unspecified, with crisis	—
D57.42	Sickle-cell thalassemia beta zero without crisis	✓
D57.43	Sickle-cell thalassemia beta zero with crisis	—
D57.44	Sickle-cell thalassemia beta plus without crisis	✓
D57.45	Sickle-cell thalassemia beta plus with crisis	—
D57.80	Other sickle-cell disorders without crisis	✓
D57.81	Other sickle-cell disorders with crisis	—
D57.211	Sickle-cell/Hb-C disease with acute chest syndrome	✓
D57.212	Sickle-cell/Hb-C disease with splenic sequestration	✓
D57.213	Sickle-cell/Hb-C disease with cerebral vascular involvement	✓
D57.214	Sickle-cell/Hb-C disease with dactylitis	✓
D57.218	Sickle-cell/Hb-C disease with crisis with other specified complication	✓
D57.219	Sickle-cell/Hb-C disease with crisis, unspecified	✓
D57.411	Sickle-cell thalassemia, unspecified, with acute chest syndrome	✓
D57.412	Sickle-cell thalassemia, unspecified, with splenic sequestration	✓
D57.413	Sickle-cell thalassemia, unspecified, with cerebral vascular involvement	✓
D57.414	Sickle-cell thalassemia, unspecified, with dactylitis	✓
D57.418	Sickle-cell thalassemia, unspecified, with crisis with other specified complication	✓
D57.419	Sickle-cell thalassemia, unspecified, with crisis	✓
D57.431	Sickle-cell thalassemia beta zero with acute chest syndrome	✓
D57.432	Sickle-cell thalassemia beta zero with splenic sequestration	✓
D57.433	Sickle-cell thalassemia beta zero with cerebral vascular involvement	✓
D57.434	Sickle-cell thalassemia beta zero with dactylitis	✓
D57.438	Sickle-cell thalassemia beta zero with crisis with other specified complication	✓
D57.439	Sickle-cell thalassemia beta zero with crisis, unspecified	✓
D57.451	Sickle-cell thalassemia beta plus with acute chest syndrome	✓
D57.452	Sickle-cell thalassemia beta plus with splenic sequestration	✓
D57.453	Sickle-cell thalassemia beta plus with cerebral vascular involvement	✓
D57.454	Sickle-cell thalassemia beta plus with dactylitis	✓
D57.458	Sickle-cell thalassemia beta plus with crisis with other specified complication	✓
D57.459	Sickle-cell thalassemia beta plus with crisis, unspecified	✓
D57.811	Other sickle-cell disorders with acute chest syndrome	✓
D57.812	Other sickle-cell disorders with splenic sequestration	✓
D57.813	Other sickle-cell disorders with cerebral vascular involvement	✓
D57.814	Other sickle-cell disorders with dactylitis	✓
D57.818	Other sickle-cell disorders with crisis with other specified complication	✓
D57.819	Other sickle-cell disorders with crisis, unspecified	✓

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Informational only, not coding or medical advice. Verify against the official ICD-10-CM (FY2026) and your payer's guidelines.

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