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ICD↔CPT crosswalk

CPT 0115U: ICD-10 codes that support medical necessity

947 covered diagnosis codes under Medicare coverage policies (LCD/NCD)

These ICD-10-CM diagnoses support medical necessity for CPT 0115U under Medicare coverage policies (LCDs, NCDs, and Billing & Coding articles). Billing CPT 0115U with a diagnosis that isn't covered typically denies as CARC 50 — not medically necessary.

National approximation. Coverage varies by MAC and state — confirm against the specific LCD/NCD and article that applies to your jurisdiction and date of service.

ICD-10Description
A00.0Cholera due to Vibrio cholerae 01, biovar cholerae
A00.1Cholera due to Vibrio cholerae 01, biovar eltor
A00.9Cholera, unspecified
A01.00Typhoid fever, unspecified
A01.01Typhoid meningitis
A01.02Typhoid fever with heart involvement
A01.03Typhoid pneumonia
A01.04Typhoid arthritis
A01.05Typhoid osteomyelitis
A01.09Typhoid fever with other complications
A01.1Paratyphoid fever A
A01.2Paratyphoid fever B
A01.3Paratyphoid fever C
A02.0Salmonella enteritis
A02.1Salmonella sepsis
A02.23Salmonella arthritis
A02.8Other specified salmonella infections
A03.0Shigellosis due to Shigella dysenteriae
A03.1Shigellosis due to Shigella flexneri
A03.2Shigellosis due to Shigella boydii
A03.3Shigellosis due to Shigella sonnei
A03.8Other shigellosis
A04.0Enteropathogenic Escherichia coli infection
A04.1Enterotoxigenic Escherichia coli infection
A04.2Enteroinvasive Escherichia coli infection
A04.3Enterohemorrhagic Escherichia coli infection
A04.5Campylobacter enteritis
A04.6Enteritis due to Yersinia enterocolitica
A04.71Enterocolitis due to Clostridium difficile, recurrent
A04.72Enterocolitis due to Clostridium difficile, not specified as recurrent
A04.8Other specified bacterial intestinal infections
A04.9Bacterial intestinal infection, unspecified
A05.0Foodborne staphylococcal intoxication
A05.1Botulism food poisoning
A05.2Foodborne Clostridium perfringens [Clostridium welchii] intoxication
A05.3Foodborne Vibrio parahaemolyticus intoxication
A05.4Foodborne Bacillus cereus intoxication
A05.5Foodborne Vibrio vulnificus intoxication
A06.0Acute amebic dysentery
A06.1Chronic intestinal amebiasis
A06.2Amebic nondysenteric colitis
A07.1Giardiasis [lambliasis]
A07.2Cryptosporidiosis
A07.4Cyclosporiasis
A08.0Rotaviral enteritis
A08.11Acute gastroenteropathy due to Norwalk agent
A08.19Acute gastroenteropathy due to other small round viruses
A08.2Adenoviral enteritis
A08.31Calicivirus enteritis
A08.32Astrovirus enteritis
A08.39Other viral enteritis
A08.8Other specified intestinal infections
A09Infectious gastroenteritis and colitis, unspecified
A32.11Listerial meningitis
A32.12Listerial meningoencephalitis
A32.7Listerial sepsis
A37.00Whooping cough due to Bordetella pertussis without pneumonia
A37.01Whooping cough due to Bordetella pertussis with pneumonia
A37.10Whooping cough due to Bordetella parapertussis without pneumonia
A37.11Whooping cough due to Bordetella parapertussis with pneumonia
A37.80Whooping cough due to other Bordetella species without pneumonia
A37.81Whooping cough due to other Bordetella species with pneumonia
A37.90Whooping cough, unspecified species without pneumonia
A37.91Whooping cough, unspecified species with pneumonia
A39.0Meningococcal meningitis
A39.81Meningococcal encephalitis
A39.9Meningococcal infection, unspecified
A40.0Sepsis due to streptococcus, group A
A40.1Sepsis due to streptococcus, group B
A40.3Sepsis due to Streptococcus pneumoniae
A40.8Other streptococcal sepsis
A40.9Streptococcal sepsis, unspecified
A41.01Sepsis due to Methicillin susceptible Staphylococcus aureus
A41.02Sepsis due to Methicillin resistant Staphylococcus aureus
A41.1Sepsis due to other specified staphylococcus
A41.2Sepsis due to unspecified staphylococcus
A41.3Sepsis due to Hemophilus influenzae
A41.4Sepsis due to anaerobes
A41.50Gram-negative sepsis, unspecified
A41.51Sepsis due to Escherichia coli [E. coli]
A41.52Sepsis due to Pseudomonas
A41.53Sepsis due to Serratia
A41.54Sepsis due to Acinetobacter baumannii
A41.59Other Gram-negative sepsis
A41.81Sepsis due to Enterococcus
A41.89Other specified sepsis
A41.9Sepsis, unspecified organism
A48.1Legionnaires' disease
A48.2Nonpneumonic Legionnaires' disease [Pontiac fever]
A51.0Primary genital syphilis
A51.1Primary anal syphilis
A51.31Condyloma latum
A52.76Other genitourinary symptomatic late syphilis
A54.00Gonococcal infection of lower genitourinary tract, unspecified
A54.01Gonococcal cystitis and urethritis, unspecified
A54.02Gonococcal vulvovaginitis, unspecified
A54.03Gonococcal cervicitis, unspecified
A54.09Other gonococcal infection of lower genitourinary tract
A54.1Gonococcal infection of lower genitourinary tract with periurethral and accessory gland abscess
A54.21Gonococcal infection of kidney and ureter
A54.22Gonococcal prostatitis
A54.23Gonococcal infection of other male genital organs
A54.24Gonococcal female pelvic inflammatory disease
A54.29Other gonococcal genitourinary infections
A54.42Gonococcal arthritis
A54.6Gonococcal infection of anus and rectum
A54.81Gonococcal meningitis
A54.86Gonococcal sepsis
A56.00Chlamydial infection of lower genitourinary tract, unspecified
A56.01Chlamydial cystitis and urethritis
A56.02Chlamydial vulvovaginitis
A56.09Other chlamydial infection of lower genitourinary tract
A56.11Chlamydial female pelvic inflammatory disease
A56.19Other chlamydial genitourinary infection
A56.2Chlamydial infection of genitourinary tract, unspecified
A56.3Chlamydial infection of anus and rectum
A59.00Urogenital trichomoniasis, unspecified
A59.01Trichomonal vulvovaginitis
A59.02Trichomonal prostatitis
A59.03Trichomonal cystitis and urethritis
A59.09Other urogenital trichomoniasis
A60.00Herpesviral infection of urogenital system, unspecified
A60.01Herpesviral infection of penis
A60.02Herpesviral infection of other male genital organs
A60.03Herpesviral cervicitis
A60.04Herpesviral vulvovaginitis
A60.09Herpesviral infection of other urogenital tract
A60.1Herpesviral infection of perianal skin and rectum
A60.9Anogenital herpesviral infection, unspecified
A63.0Anogenital (venereal) warts
A77.40Ehrlichiosis, unspecified
A77.41Ehrlichiosis chaffeensis [E. chaffeensis]
A77.49Other ehrlichiosis
A79.82Anaplasmosis [A. phagocytophilum]
A79.9Rickettsiosis, unspecified
A80.0Acute paralytic poliomyelitis, vaccine-associated
A80.1Acute paralytic poliomyelitis, wild virus, imported
A80.2Acute paralytic poliomyelitis, wild virus, indigenous
A80.30Acute paralytic poliomyelitis, unspecified
A80.39Other acute paralytic poliomyelitis
A80.4Acute nonparalytic poliomyelitis
A80.9Acute poliomyelitis, unspecified
A84.89Other tick-borne viral encephalitis
A84.9Tick-borne viral encephalitis, unspecified
A85.0Enteroviral encephalitis
A85.1Adenoviral encephalitis
A85.2Arthropod-borne viral encephalitis, unspecified
A85.8Other specified viral encephalitis
A86Unspecified viral encephalitis
A87.0Enteroviral meningitis
A87.8Other viral meningitis
A87.9Viral meningitis, unspecified
A93.8Other specified arthropod-borne viral fevers
A94Unspecified arthropod-borne viral fever
B00.0Eczema herpeticum
B00.1Herpesviral vesicular dermatitis
B00.2Herpesviral gingivostomatitis and pharyngotonsillitis
B00.3Herpesviral meningitis
B00.4Herpesviral encephalitis
B00.59Other herpesviral disease of eye
B01.0Varicella meningitis
B01.11Varicella encephalitis and encephalomyelitis
B01.81Varicella keratitis
B01.9Varicella without complication
B02.1Zoster meningitis
B02.30Zoster ocular disease, unspecified
B02.31Zoster conjunctivitis
B02.32Zoster iridocyclitis
B02.33Zoster keratitis
B02.34Zoster scleritis
B02.39Other herpes zoster eye disease
B02.7Disseminated zoster
B02.8Zoster with other complications
B10.01Human herpesvirus 6 encephalitis
B20Human immunodeficiency virus [HIV] disease
B25.0Cytomegaloviral pneumonitis
B25.1Cytomegaloviral hepatitis
B25.2Cytomegaloviral pancreatitis
B27.02Gammaherpesviral mononucleosis with meningitis
B27.12Cytomegaloviral mononucleosis with meningitis
B27.82Other infectious mononucleosis with meningitis
B33.23Viral pericarditis
B33.24Viral cardiomyopathy
B35.1Tinea unguium
B37.31Acute candidiasis of vulva and vagina
B37.32Chronic candidiasis of vulva and vagina
B37.41Candidal cystitis and urethritis
B37.42Candidal balanitis
B37.49Other urogenital candidiasis
B37.5Candidal meningitis
B37.7Candidal sepsis
B37.89Other sites of candidiasis
B45.1Cerebral cryptococcosis
B59Pneumocystosis
B60.00Babesiosis, unspecified
B60.01Babesiosis due to Babesia microti
B60.02Babesiosis due to Babesia duncani
B60.03Babesiosis due to Babesia divergens
B60.09Other babesiosis
B60.2Naegleriasis
B88.09Other acariasis
B96.83Acinetobacter baumannii as the cause of diseases classified elsewhere
B97.21SARS-associated coronavirus as the cause of diseases classified elsewhere
B97.29Other coronavirus as the cause of diseases classified elsewhere
B97.35Human immunodeficiency virus, type 2 [HIV 2] as the cause of diseases classified elsewhere
B99.9Unspecified infectious disease
C46.0Kaposi's sarcoma of skin
C46.1Kaposi's sarcoma of soft tissue
C46.2Kaposi's sarcoma of palate
C46.3Kaposi's sarcoma of lymph nodes
C46.4Kaposi's sarcoma of gastrointestinal sites
C46.50Kaposi's sarcoma of unspecified lung
C46.51Kaposi's sarcoma of right lung
C46.52Kaposi's sarcoma of left lung
C46.7Kaposi's sarcoma of other sites
D26.0Other benign neoplasm of cervix uteri
D57.01Hb-SS disease with acute chest syndrome
D59.30Hemolytic-uremic syndrome, unspecified
D59.31Infection-associated hemolytic-uremic syndrome
D61.03Fanconi anemia
D61.09Other constitutional aplastic anemia
D61.1Drug-induced aplastic anemia
D61.2Aplastic anemia due to other external agents
D61.3Idiopathic aplastic anemia
D61.810Antineoplastic chemotherapy induced pancytopenia
D61.811Other drug-induced pancytopenia
D61.818Other pancytopenia
D61.82Myelophthisis
D61.89Other specified aplastic anemias and other bone marrow failure syndromes
D61.9Aplastic anemia, unspecified
D64.81Anemia due to antineoplastic chemotherapy
D64.89Other specified anemias
D70.0Congenital agranulocytosis
D70.1Agranulocytosis secondary to cancer chemotherapy
D70.2Other drug-induced agranulocytosis
D70.3Neutropenia due to infection
D70.4Cyclic neutropenia
D70.9Neutropenia, unspecified
D71.1Leukocyte adhesion deficiency
D71.8Other functional disorders of polymorphonuclear neutrophils
D71.9Functional disorders of polymorphonuclear neutrophils, unspecified
D80.0Hereditary hypogammaglobulinemia
D80.1Nonfamilial hypogammaglobulinemia
D80.2Selective deficiency of immunoglobulin A [IgA]
D80.3Selective deficiency of immunoglobulin G [IgG] subclasses
D80.4Selective deficiency of immunoglobulin M [IgM]
D80.5Immunodeficiency with increased immunoglobulin M [IgM]
D80.6Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinemia
D80.8Other immunodeficiencies with predominantly antibody defects
D80.9Immunodeficiency with predominantly antibody defects, unspecified
D81.0Severe combined immunodeficiency [SCID] with reticular dysgenesis
D81.1Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
D81.2Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
D81.30Adenosine deaminase deficiency, unspecified
D81.31Severe combined immunodeficiency due to adenosine deaminase deficiency
D81.32Adenosine deaminase 2 deficiency
D81.39Other adenosine deaminase deficiency
D81.4Nezelof's syndrome
D81.5Purine nucleoside phosphorylase [PNP] deficiency
D81.6Major histocompatibility complex class I deficiency
D81.7Major histocompatibility complex class II deficiency
D81.810Biotinidase deficiency
D81.818Other biotin-dependent carboxylase deficiency
D81.82Activated Phosphoinositide 3-kinase Delta Syndrome [APDS]
D81.89Other combined immunodeficiencies
D81.9Combined immunodeficiency, unspecified
D82.0Wiskott-Aldrich syndrome
D82.1Di George's syndrome
D82.2Immunodeficiency with short-limbed stature
D82.3Immunodeficiency following hereditary defective response to Epstein-Barr virus
D82.4Hyperimmunoglobulin E [IgE] syndrome
D82.8Immunodeficiency associated with other specified major defects
D83.0Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
D83.1Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
D83.2Common variable immunodeficiency with autoantibodies to B- or T-cells
D83.8Other common variable immunodeficiencies
D83.9Common variable immunodeficiency, unspecified
D84.0Lymphocyte function antigen-1 [LFA-1] defect
D84.1Defects in the complement system
D84.821Immunodeficiency due to drugs
D84.822Immunodeficiency due to external causes
D84.89Other immunodeficiencies
D84.9Immunodeficiency, unspecified
D89.0Polyclonal hypergammaglobulinemia
D89.1Cryoglobulinemia
D89.2Hypergammaglobulinemia, unspecified
D89.3Immune reconstitution syndrome
D89.41Monoclonal mast cell activation syndrome
D89.42Idiopathic mast cell activation syndrome
D89.43Secondary mast cell activation
D89.44Hereditary alpha tryptasemia
D89.49Other mast cell activation disorder
D89.810Acute graft-versus-host disease
D89.811Chronic graft-versus-host disease
D89.812Acute on chronic graft-versus-host disease
D89.813Graft-versus-host disease, unspecified
D89.82Autoimmune lymphoproliferative syndrome [ALPS]
D89.89Other specified disorders involving the immune mechanism, not elsewhere classified
E08.43Diabetes mellitus due to underlying condition with diabetic autonomic (poly)neuropathy
E08.52Diabetes mellitus due to underlying condition with diabetic peripheral angiopathy with gangrene
E10.43Type 1 diabetes mellitus with diabetic autonomic (poly)neuropathy
E10.52Type 1 diabetes mellitus with diabetic peripheral angiopathy with gangrene
E11.43Type 2 diabetes mellitus with diabetic autonomic (poly)neuropathy
E11.52Type 2 diabetes mellitus with diabetic peripheral angiopathy with gangrene
E13.43Other specified diabetes mellitus with diabetic autonomic (poly)neuropathy
E84.0Cystic fibrosis with pulmonary manifestations
E84.19Cystic fibrosis with other intestinal manifestations
E84.8Cystic fibrosis with other manifestations
G00.0Hemophilus meningitis
G00.1Pneumococcal meningitis
G00.2Streptococcal meningitis
G00.8Other bacterial meningitis
G00.9Bacterial meningitis, unspecified
G03.0Nonpyogenic meningitis
G03.9Meningitis, unspecified
G04.01Postinfectious acute disseminated encephalitis and encephalomyelitis (postinfectious ADEM)
G04.02Postimmunization acute disseminated encephalitis, myelitis and encephalomyelitis
G04.30Acute necrotizing hemorrhagic encephalopathy, unspecified
G04.31Postinfectious acute necrotizing hemorrhagic encephalopathy
G04.32Postimmunization acute necrotizing hemorrhagic encephalopathy
G04.39Other acute necrotizing hemorrhagic encephalopathy
G04.81Other encephalitis and encephalomyelitis
G04.82Acute flaccid myelitis
G04.89Other myelitis
G04.90Encephalitis and encephalomyelitis, unspecified
G04.91Myelitis, unspecified
G05.3Encephalitis and encephalomyelitis in diseases classified elsewhere
G05.4Myelitis in diseases classified elsewhere
I27.0Primary pulmonary hypertension
I27.21Secondary pulmonary arterial hypertension
I27.22Pulmonary hypertension due to left heart disease
I27.23Pulmonary hypertension due to lung diseases and hypoxia
I27.24Chronic thromboembolic pulmonary hypertension
I27.29Other secondary pulmonary hypertension
I27.81Cor pulmonale (chronic)
I27.82Chronic pulmonary embolism
I27.83Eisenmenger's syndrome
I27.89Other specified pulmonary heart diseases
I33.0Acute and subacute infective endocarditis
I50.21Acute systolic (congestive) heart failure
I50.22Chronic systolic (congestive) heart failure
I50.23Acute on chronic systolic (congestive) heart failure
I50.31Acute diastolic (congestive) heart failure
I50.32Chronic diastolic (congestive) heart failure
I50.33Acute on chronic diastolic (congestive) heart failure
I50.41Acute combined systolic (congestive) and diastolic (congestive) heart failure
I50.42Chronic combined systolic (congestive) and diastolic (congestive) heart failure
I50.43Acute on chronic combined systolic (congestive) and diastolic (congestive) heart failure
I50.811Acute right heart failure
I50.812Chronic right heart failure
I50.813Acute on chronic right heart failure
I50.814Right heart failure due to left heart failure
I50.82Biventricular heart failure
I50.83High output heart failure
I50.84End stage heart failure
I50.89Other heart failure
J00Acute nasopharyngitis [common cold]
J02.9Acute pharyngitis, unspecified
J04.0Acute laryngitis
J04.10Acute tracheitis without obstruction
J04.11Acute tracheitis with obstruction
J04.2Acute laryngotracheitis
J04.30Supraglottitis, unspecified, without obstruction
J04.31Supraglottitis, unspecified, with obstruction
J05.0Acute obstructive laryngitis [croup]
J05.10Acute epiglottitis without obstruction
J05.11Acute epiglottitis with obstruction
J06.0Acute laryngopharyngitis
J06.9Acute upper respiratory infection, unspecified
J09.X1Influenza due to identified novel influenza A virus with pneumonia
J09.X2Influenza due to identified novel influenza A virus with other respiratory manifestations
J09.X3Influenza due to identified novel influenza A virus with gastrointestinal manifestations
J09.X9Influenza due to identified novel influenza A virus with other manifestations
J10.01Influenza due to other identified influenza virus with the same other identified influenza virus pneumonia
J10.08Influenza due to other identified influenza virus with other specified pneumonia
J10.1Influenza due to other identified influenza virus with other respiratory manifestations
J10.2Influenza due to other identified influenza virus with gastrointestinal manifestations
J10.81Influenza due to other identified influenza virus with encephalopathy
J10.82Influenza due to other identified influenza virus with myocarditis
J10.83Influenza due to other identified influenza virus with otitis media
J10.89Influenza due to other identified influenza virus with other manifestations
J11.08Influenza due to unidentified influenza virus with specified pneumonia
J11.1Influenza due to unidentified influenza virus with other respiratory manifestations
J11.2Influenza due to unidentified influenza virus with gastrointestinal manifestations
J11.81Influenza due to unidentified influenza virus with encephalopathy
J11.82Influenza due to unidentified influenza virus with myocarditis
J11.83Influenza due to unidentified influenza virus with otitis media
J11.89Influenza due to unidentified influenza virus with other manifestations
J12.0Adenoviral pneumonia
J12.1Respiratory syncytial virus pneumonia
J12.2Parainfluenza virus pneumonia
J12.3Human metapneumovirus pneumonia
J12.81Pneumonia due to SARS-associated coronavirus
J12.82Pneumonia due to coronavirus disease 2019
J12.89Other viral pneumonia
J12.9Viral pneumonia, unspecified
J13Pneumonia due to Streptococcus pneumoniae
J15.0Pneumonia due to Klebsiella pneumoniae
J15.1Pneumonia due to Pseudomonas
J15.20Pneumonia due to staphylococcus, unspecified

Showing the first 400 of 947 covered codes — this procedure has a large covered-diagnosis set; see the governing LCD/article for the complete list.

Frequently asked questions

Which ICD-10 codes support medical necessity for CPT 0115U?

Medicare coverage policies (LCDs/NCDs and Billing & Coding articles) list 947 ICD-10 diagnosis codes that support medical necessity for CPT 0115U. The covered codes are listed on this page. Coverage varies by MAC/state — always confirm against the policy that applies to you.

What is a medical-necessity (LCD/NCD) crosswalk?

A claim whose procedure isn't supported by a covered diagnosis denies as "not medically necessary" (CARC 50). CMS coverage policies define which diagnoses justify a procedure; this page is the ICD-10 → CPT 0115U view of that relationship.

Catch medical-necessity denials before you bill. CareNiva scrubs claims against LCD/NCD coverage and flags unsupported diagnoses — in the same platform you run visits and billing.

More free billing tools: all crosswalks · NCCI edits · Medicare fees · denial codes

Informational only, not coding, billing, or legal advice. Based on CMS Medicare Coverage Database data; verify the current LCD/NCD for your MAC before billing.

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