R65.11: Systemic inflammatory response syndrome (SIRS) of non-infectious origin with acute organ dysfunction
R65.11 is the billable ICD-10-CM diagnosis code for Systemic inflammatory response syndrome (SIRS) of non-infectious origin with acute organ dysfunction. It is a fully specified code, so it can be reported on a claim (subject to clinical documentation and your payer's rules).
Frequently asked questions
What is ICD-10-CM code R65.11?
R65.11 is the ICD-10-CM diagnosis code for Systemic inflammatory response syndrome (SIRS) of non-infectious origin with acute organ dysfunction. It belongs to category R65 (Symptoms and signs specifically associated with systemic inflammation and infection).
Is R65.11 a billable code?
Yes. R65.11 is a billable, fully specified ICD-10-CM code, so it can be used on a claim (subject to documentation and payer rules).
What category does R65.11 belong to?
R65.11 is part of ICD-10-CM category R65 — Symptoms and signs specifically associated with systemic inflammation and infection, which has 8 billable codes.
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Informational only, not coding or medical advice. Verify against the official ICD-10-CM (FY2026) and your payer's guidelines.
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