R65.10: Systemic inflammatory response syndrome (SIRS) of non-infectious origin without acute organ dysfunction
R65.10 is the billable ICD-10-CM diagnosis code for Systemic inflammatory response syndrome (SIRS) of non-infectious origin without acute organ dysfunction. It is a fully specified code, so it can be reported on a claim (subject to clinical documentation and your payer's rules).
Frequently asked questions
What is ICD-10-CM code R65.10?
R65.10 is the ICD-10-CM diagnosis code for Systemic inflammatory response syndrome (SIRS) of non-infectious origin without acute organ dysfunction. It belongs to category R65 (Symptoms and signs specifically associated with systemic inflammation and infection).
Is R65.10 a billable code?
Yes. R65.10 is a billable, fully specified ICD-10-CM code, so it can be used on a claim (subject to documentation and payer rules).
What category does R65.10 belong to?
R65.10 is part of ICD-10-CM category R65 — Symptoms and signs specifically associated with systemic inflammation and infection, which has 8 billable codes.
More free billing tools: all ICD-10 categories · ICD-10 search · denial codes · Medicare fees
Informational only, not coding or medical advice. Verify against the official ICD-10-CM (FY2026) and your payer's guidelines.
Code the diagnosis right
Join providers across the country delivering modern virtual care with CareNiva. Free to start, ready in minutes.
100% Satisfaction Guaranteed — try it risk-free