D81.6: Major histocompatibility complex class I deficiency
D81.6 is the billable ICD-10-CM diagnosis code for Major histocompatibility complex class I deficiency. It is a fully specified code, so it can be reported on a claim (subject to clinical documentation and your payer's rules).
Frequently asked questions
What is ICD-10-CM code D81.6?
D81.6 is the ICD-10-CM diagnosis code for Major histocompatibility complex class I deficiency. It belongs to category D81 (Combined immunodeficiencies).
Is D81.6 a billable code?
Yes. D81.6 is a billable, fully specified ICD-10-CM code, so it can be used on a claim (subject to documentation and payer rules).
What category does D81.6 belong to?
D81.6 is part of ICD-10-CM category D81 — Combined immunodeficiencies, which has 34 billable codes.
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Informational only, not coding or medical advice. Verify against the official ICD-10-CM (FY2026) and your payer's guidelines.
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