ICD↔CPT crosswalk
CPT J1553: ICD-10 codes that support medical necessity
These ICD-10-CM diagnoses support medical necessity for CPT J1553 under Medicare coverage policies (LCDs, NCDs, and Billing & Coding articles). Billing CPT J1553 with a diagnosis that isn't covered typically denies as CARC 50 — not medically necessary.
National approximation. Coverage varies by MAC and state — confirm against the specific LCD/NCD and article that applies to your jurisdiction and date of service.
| ICD-10 | Description |
|---|---|
| B20 | Human immunodeficiency virus [HIV] disease |
| B25.0 | Cytomegaloviral pneumonitis |
| B25.1 | Cytomegaloviral hepatitis |
| B25.2 | Cytomegaloviral pancreatitis |
| B25.8 | Other cytomegaloviral diseases |
| C90.00 | Multiple myeloma not having achieved remission |
| C90.02 | Multiple myeloma in relapse |
| C91.10 | Chronic lymphocytic leukemia of B-cell type not having achieved remission |
| C91.11 | Chronic lymphocytic leukemia of B-cell type in remission |
| C91.12 | Chronic lymphocytic leukemia of B-cell type in relapse |
| D59.0 | Drug-induced autoimmune hemolytic anemia |
| D59.11 | Warm autoimmune hemolytic anemia |
| D59.12 | Cold autoimmune hemolytic anemia |
| D59.13 | Mixed type autoimmune hemolytic anemia |
| D59.19 | Other autoimmune hemolytic anemia |
| D61.01 | Constitutional (pure) red blood cell aplasia |
| D69.3 | Immune thrombocytopenic purpura |
| D69.41 | Evans syndrome |
| D69.42 | Congenital and hereditary thrombocytopenia purpura |
| D69.49 | Other primary thrombocytopenia |
| D80.0 | Hereditary hypogammaglobulinemia |
| D80.1 | Nonfamilial hypogammaglobulinemia |
| D80.2 | Selective deficiency of immunoglobulin A [IgA] |
| D80.3 | Selective deficiency of immunoglobulin G [IgG] subclasses |
| D80.4 | Selective deficiency of immunoglobulin M [IgM] |
| D80.5 | Immunodeficiency with increased immunoglobulin M [IgM] |
| D80.6 | Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinemia |
| D80.7 | Transient hypogammaglobulinemia of infancy |
| D80.8 | Other immunodeficiencies with predominantly antibody defects |
| D81.0 | Severe combined immunodeficiency [SCID] with reticular dysgenesis |
| D81.1 | Severe combined immunodeficiency [SCID] with low T- and B-cell numbers |
| D81.2 | Severe combined immunodeficiency [SCID] with low or normal B-cell numbers |
| D81.31 | Severe combined immunodeficiency due to adenosine deaminase deficiency |
| D81.4 | Nezelof's syndrome |
| D81.5 | Purine nucleoside phosphorylase [PNP] deficiency |
| D81.6 | Major histocompatibility complex class I deficiency |
| D81.7 | Major histocompatibility complex class II deficiency |
| D81.82 | Activated Phosphoinositide 3-kinase Delta Syndrome [APDS] |
| D81.89 | Other combined immunodeficiencies |
| D81.9 | Combined immunodeficiency, unspecified |
| D82.0 | Wiskott-Aldrich syndrome |
| D82.1 | Di George's syndrome |
| D82.4 | Hyperimmunoglobulin E [IgE] syndrome |
| D83.0 | Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function |
| D83.1 | Common variable immunodeficiency with predominant immunoregulatory T-cell disorders |
| D83.2 | Common variable immunodeficiency with autoantibodies to B- or T-cells |
| D83.8 | Other common variable immunodeficiencies |
| D83.9 | Common variable immunodeficiency, unspecified |
| G04.81 | Other encephalitis and encephalomyelitis |
| G11.3 | Cerebellar ataxia with defective DNA repair |
| G25.82 | Stiff-man syndrome |
| G35.A | Relapsing-remitting multiple sclerosis |
| G35.B1 | Active primary progressive multiple sclerosis |
| G35.B2 | Non-active primary progressive multiple sclerosis |
| G35.C1 | Active secondary progressive multiple sclerosis |
| G35.C2 | Non-active secondary progressive multiple sclerosis |
| G36.0 | Neuromyelitis optica [Devic] |
| G60.3 | Idiopathic progressive neuropathy |
| G61.0 | Guillain-Barre syndrome |
| G61.81 | Chronic inflammatory demyelinating polyneuritis |
| G61.82 | Multifocal motor neuropathy |
| G65.0 | Sequelae of Guillain-Barre syndrome |
| G70.00 | Myasthenia gravis without (acute) exacerbation |
| G70.01 | Myasthenia gravis with (acute) exacerbation |
| G70.80 | Lambert-Eaton syndrome, unspecified |
| G70.81 | Lambert-Eaton syndrome in disease classified elsewhere |
| G72.41 | Inclusion body myositis [IBM] |
| G72.81 | Critical illness myopathy |
| G72.89 | Other specified myopathies |
| G73.1 | Lambert-Eaton syndrome in neoplastic disease |
| G73.3 | Myasthenic syndromes in other diseases classified elsewhere |
| G93.49 | Other encephalopathy |
| H05.241 | Constant exophthalmos, right eye |
| H05.242 | Constant exophthalmos, left eye |
| H05.243 | Constant exophthalmos, bilateral |
| I78.8 | Other diseases of capillaries |
| L10.0 | Pemphigus vulgaris |
| L10.1 | Pemphigus vegetans |
| L10.2 | Pemphigus foliaceous |
| L10.3 | Brazilian pemphigus [fogo selvagem] |
| L10.4 | Pemphigus erythematosus |
| L10.5 | Drug-induced pemphigus |
| L10.81 | Paraneoplastic pemphigus |
| L10.89 | Other pemphigus |
| L10.9 | Pemphigus, unspecified |
| L12.0 | Bullous pemphigoid |
| L12.1 | Cicatricial pemphigoid |
| L12.35 | Other acquired epidermolysis bullosa |
| L12.8 | Other pemphigoid |
| L12.9 | Pemphigoid, unspecified |
| L13.8 | Other specified bullous disorders |
| L51.1 | Stevens-Johnson syndrome |
| L51.2 | Toxic epidermal necrolysis [Lyell] |
| L51.3 | Stevens-Johnson syndrome-toxic epidermal necrolysis overlap syndrome |
| L98.5 | Mucinosis of the skin |
| M30.3 | Mucocutaneous lymph node syndrome [Kawasaki] |
| M31.10 | Thrombotic microangiopathy, unspecified |
| M31.19 | Other thrombotic microangiopathy |
| M32.11 | Endocarditis in systemic lupus erythematosus |
| M32.12 | Pericarditis in systemic lupus erythematosus |
| M32.13 | Lung involvement in systemic lupus erythematosus |
| M32.14 | Glomerular disease in systemic lupus erythematosus |
| M32.15 | Tubulo-interstitial nephropathy in systemic lupus erythematosus |
| M32.19 | Other organ or system involvement in systemic lupus erythematosus |
| M33.00 | Juvenile dermatomyositis, organ involvement unspecified |
| M33.01 | Juvenile dermatomyositis with respiratory involvement |
| M33.02 | Juvenile dermatomyositis with myopathy |
| M33.03 | Juvenile dermatomyositis without myopathy |
| M33.09 | Juvenile dermatomyositis with other organ involvement |
| M33.10 | Other dermatomyositis, organ involvement unspecified |
| M33.11 | Other dermatomyositis with respiratory involvement |
| M33.12 | Other dermatomyositis with myopathy |
| M33.13 | Other dermatomyositis without myopathy |
| M33.19 | Other dermatomyositis with other organ involvement |
| M33.20 | Polymyositis, organ involvement unspecified |
| M33.21 | Polymyositis with respiratory involvement |
| M33.22 | Polymyositis with myopathy |
| M33.29 | Polymyositis with other organ involvement |
| M33.90 | Dermatopolymyositis, unspecified, organ involvement unspecified |
| M33.91 | Dermatopolymyositis, unspecified with respiratory involvement |
| M33.92 | Dermatopolymyositis, unspecified with myopathy |
| M33.99 | Dermatopolymyositis, unspecified with other organ involvement |
| M34.83 | Systemic sclerosis with polyneuropathy |
| M36.0 | Dermato(poly)myositis in neoplastic disease |
| N18.6 | End stage renal disease |
| T86.01 | Bone marrow transplant rejection |
| T86.02 | Bone marrow transplant failure |
| T86.09 | Other complications of bone marrow transplant |
| T86.11 | Kidney transplant rejection |
| T86.12 | Kidney transplant failure |
| T86.19 | Other complication of kidney transplant |
| T86.21 | Heart transplant rejection |
| T86.22 | Heart transplant failure |
| T86.298 | Other complications of heart transplant |
| T86.31 | Heart-lung transplant rejection |
| T86.41 | Liver transplant rejection |
| T86.5 | Complications of stem cell transplant |
| T86.810 | Lung transplant rejection |
| Z48.21 | Encounter for aftercare following heart transplant |
| Z48.22 | Encounter for aftercare following kidney transplant |
| Z51.11 | Encounter for antineoplastic chemotherapy |
| Z51.12 | Encounter for antineoplastic immunotherapy |
| Z76.82 | Awaiting organ transplant status |
| Z86.19 | Personal history of other infectious and parasitic diseases |
| Z87.01 | Personal history of pneumonia (recurrent) |
| Z94.0 | Kidney transplant status |
| Z94.1 | Heart transplant status |
| Z94.81 | Bone marrow transplant status |
| Z94.84 | Stem cells transplant status |
Frequently asked questions
Which ICD-10 codes support medical necessity for CPT J1553?
Medicare coverage policies (LCDs/NCDs and Billing & Coding articles) list 149 ICD-10 diagnosis codes that support medical necessity for CPT J1553. The covered codes are listed on this page. Coverage varies by MAC/state — always confirm against the policy that applies to you.
What is a medical-necessity (LCD/NCD) crosswalk?
A claim whose procedure isn't supported by a covered diagnosis denies as "not medically necessary" (CARC 50). CMS coverage policies define which diagnoses justify a procedure; this page is the ICD-10 → CPT J1553 view of that relationship.
Catch medical-necessity denials before you bill. CareNiva scrubs claims against LCD/NCD coverage and flags unsupported diagnoses — in the same platform you run visits and billing.
More free billing tools: all crosswalks · NCCI edits · Medicare fees · denial codes
Informational only, not coding, billing, or legal advice. Based on CMS Medicare Coverage Database data; verify the current LCD/NCD for your MAC before billing.
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