Z17: Estrogen, and other hormones and factors receptor status
Codes under Z17 (Estrogen, and other hormones and factors receptor status). A ✓ marks a billable (fully specified) code; category codes without a ✓ are not billable on their own.
| Code | Description | Billable |
|---|---|---|
| Z17.0 | Estrogen receptor positive status [ER+] | ✓ |
| Z17.0 | Estrogen receptor positive status [ER+] | ✓ |
| Z17.1 | Estrogen receptor negative status [ER-] | ✓ |
| Z17.1 | Estrogen receptor negative status [ER-] | ✓ |
| Z17.2 | Progesterone receptor status | — |
| Z17.2 | Progesterone receptor status | — |
| Z17.3 | Human epidermal growth factor 2 receptor | — |
| Z17.3 | Human epidermal growth factor 2 receptor | — |
| Z17.4 | Combined receptor status | — |
| Z17.4 | Combined receptor status | — |
| Z17.21 | Progesterone receptor positive status | ✓ |
| Z17.21 | Progesterone receptor positive status | ✓ |
| Z17.22 | Progesterone receptor negative status | ✓ |
| Z17.22 | Progesterone receptor negative status | ✓ |
| Z17.31 | Human epidermal growth factor receptor 2 positive status | ✓ |
| Z17.31 | Human epidermal growth factor receptor 2 positive status | ✓ |
| Z17.32 | Human epidermal growth factor receptor 2 negative status | ✓ |
| Z17.32 | Human epidermal growth factor receptor 2 negative status | ✓ |
| Z17.41 | Hormone receptor positive | — |
| Z17.41 | Hormone receptor positive | — |
| Z17.42 | Hormone receptor negative | — |
| Z17.42 | Hormone receptor negative | — |
| Z17.410 | Hormone receptor positive with human epidermal growth factor receptor 2 positive status | ✓ |
| Z17.410 | Hormone receptor positive with human epidermal growth factor receptor 2 positive status | ✓ |
| Z17.411 | Hormone receptor positive with human epidermal growth factor receptor 2 negative status | ✓ |
| Z17.411 | Hormone receptor positive with human epidermal growth factor receptor 2 negative status | ✓ |
| Z17.420 | Hormone receptor negative with human epidermal growth factor receptor 2 positive status | ✓ |
| Z17.420 | Hormone receptor negative with human epidermal growth factor receptor 2 positive status | ✓ |
| Z17.421 | Hormone receptor negative with human epidermal growth factor receptor 2 negative status | ✓ |
| Z17.421 | Hormone receptor negative with human epidermal growth factor receptor 2 negative status | ✓ |
Frequently asked questions
What is ICD-10-CM code Z17?
Z17 is an ICD-10-CM category covering Estrogen, and other hormones and factors receptor status. It contains 30 more specific diagnosis codes, 20 of which are billable.
Is Z17 a billable code?
No — Z17 is a category header and isn't billable on its own. Code to the highest level of specificity using one of its subcodes (for example Z17.0 — Estrogen receptor positive status [ER+]). 20 of the 30 codes under Z17 are billable.
What codes fall under Z17?
Z17 includes Z17.0, Z17.0, Z17.1, Z17.1, Z17.2, plus 25 more. See the full list with descriptions and billable status above.
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Informational only, not coding or medical advice. Verify against the official ICD-10-CM (FY2026) and your payer's guidelines.
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