Z16: Resistance to antimicrobial drugs

Codes under Z16 (Resistance to antimicrobial drugs). A ✓ marks a billable (fully specified) code; category codes without a ✓ are not billable on their own.

Code	Description	Billable
Z16.1	Resistance to beta lactam antibiotics	—
Z16.2	Resistance to other antibiotics	—
Z16.3	Resistance to other antimicrobial drugs	—
Z16.10	Resistance to unspecified beta lactam antibiotics	✓
Z16.11	Resistance to penicillins	✓
Z16.12	Extended spectrum beta lactamase (ESBL) resistance	✓
Z16.13	Resistance to carbapenem	✓
Z16.19	Resistance to other specified beta lactam antibiotics	✓
Z16.20	Resistance to unspecified antibiotic	✓
Z16.21	Resistance to vancomycin	✓
Z16.22	Resistance to vancomycin related antibiotics	✓
Z16.23	Resistance to quinolones and fluoroquinolones	✓
Z16.24	Resistance to multiple antibiotics	✓
Z16.29	Resistance to other single specified antibiotic	✓
Z16.30	Resistance to unspecified antimicrobial drugs	✓
Z16.31	Resistance to antiparasitic drug(s)	✓
Z16.32	Resistance to antifungal drug(s)	✓
Z16.33	Resistance to antiviral drug(s)	✓
Z16.34	Resistance to antimycobacterial drug(s)	—
Z16.35	Resistance to multiple antimicrobial drugs	✓
Z16.39	Resistance to other specified antimicrobial drug	✓
Z16.341	Resistance to single antimycobacterial drug	✓
Z16.342	Resistance to multiple antimycobacterial drugs	✓

More free billing tools: all ICD-10 categories · ICD-10 search · denial codes · Medicare fees

Informational only, not coding or medical advice. Verify against the official ICD-10-CM (FY2026) and your payer's guidelines.

Code the diagnosis right