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ICD↔CPT crosswalk

CPT J1299: ICD-10 codes that support medical necessity

18 covered diagnosis codes under Medicare coverage policies (LCD/NCD)

These ICD-10-CM diagnoses support medical necessity for CPT J1299 under Medicare coverage policies (LCDs, NCDs, and Billing & Coding articles). Billing CPT J1299 with a diagnosis that isn't covered typically denies as CARC 50 — not medically necessary.

National approximation. Coverage varies by MAC and state — confirm against the specific LCD/NCD and article that applies to your jurisdiction and date of service.

ICD-10Description
D59.31Infection-associated hemolytic-uremic syndrome
D59.32Hereditary hemolytic-uremic syndrome
D59.39Other hemolytic-uremic syndrome
D59.5Paroxysmal nocturnal hemoglobinuria [Marchiafava-Micheli]
G36.0Neuromyelitis optica [Devic]
G70.00Myasthenia gravis without (acute) exacerbation
G70.01Myasthenia gravis with (acute) exacerbation
N00.6Acute nephritic syndrome with dense deposit disease
N00.B1Acute nephritic syndrome with idiopathic immune membranoproliferative glomerulonephritis (IC-MPGN)
N00.B2Acute nephritic syndrome with secondary immune complex membranoproliferative glomerulonephritis (IC-MPGN)
N01.6Rapidly progressive nephritic syndrome with dense deposit disease
N02.6Recurrent and persistent hematuria with dense deposit disease
N03.6Chronic nephritic syndrome with dense deposit disease
N04.6Nephrotic syndrome with dense deposit disease
N04.B1Nephrotic syndrome with idiopathic immune complex membranoproliferative glomerulonephritis (IC-MPGN)
N04.B2Nephrotic syndrome with secondary immune complex membranoproliferative glomerulonephritis (IC-MPGN)
N07.6Hereditary nephropathy, not elsewhere classified with dense deposit disease
T86.19Other complication of kidney transplant

Frequently asked questions

Which ICD-10 codes support medical necessity for CPT J1299?

Medicare coverage policies (LCDs/NCDs and Billing & Coding articles) list 18 ICD-10 diagnosis codes that support medical necessity for CPT J1299. The covered codes are listed on this page. Coverage varies by MAC/state — always confirm against the policy that applies to you.

What is a medical-necessity (LCD/NCD) crosswalk?

A claim whose procedure isn't supported by a covered diagnosis denies as "not medically necessary" (CARC 50). CMS coverage policies define which diagnoses justify a procedure; this page is the ICD-10 → CPT J1299 view of that relationship.

Catch medical-necessity denials before you bill. CareNiva scrubs claims against LCD/NCD coverage and flags unsupported diagnoses — in the same platform you run visits and billing.

More free billing tools: all crosswalks · NCCI edits · Medicare fees · denial codes

Informational only, not coding, billing, or legal advice. Based on CMS Medicare Coverage Database data; verify the current LCD/NCD for your MAC before billing.

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