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ICD↔CPT crosswalk

CPT 76641: ICD-10 codes that support medical necessity

173 covered diagnosis codes under Medicare coverage policies (LCD/NCD)

These ICD-10-CM diagnoses support medical necessity for CPT 76641 under Medicare coverage policies (LCDs, NCDs, and Billing & Coding articles). Billing CPT 76641 with a diagnosis that isn't covered typically denies as CARC 50 — not medically necessary.

National approximation. Coverage varies by MAC and state — confirm against the specific LCD/NCD and article that applies to your jurisdiction and date of service.

ICD-10Description
C45.9Mesothelioma, unspecified
C50.011Malignant neoplasm of nipple and areola, right female breast
C50.012Malignant neoplasm of nipple and areola, left female breast
C50.021Malignant neoplasm of nipple and areola, right male breast
C50.022Malignant neoplasm of nipple and areola, left male breast
C50.111Malignant neoplasm of central portion of right female breast
C50.112Malignant neoplasm of central portion of left female breast
C50.121Malignant neoplasm of central portion of right male breast
C50.122Malignant neoplasm of central portion of left male breast
C50.211Malignant neoplasm of upper-inner quadrant of right female breast
C50.212Malignant neoplasm of upper-inner quadrant of left female breast
C50.221Malignant neoplasm of upper-inner quadrant of right male breast
C50.222Malignant neoplasm of upper-inner quadrant of left male breast
C50.311Malignant neoplasm of lower-inner quadrant of right female breast
C50.312Malignant neoplasm of lower-inner quadrant of left female breast
C50.321Malignant neoplasm of lower-inner quadrant of right male breast
C50.322Malignant neoplasm of lower-inner quadrant of left male breast
C50.411Malignant neoplasm of upper-outer quadrant of right female breast
C50.412Malignant neoplasm of upper-outer quadrant of left female breast
C50.421Malignant neoplasm of upper-outer quadrant of right male breast
C50.422Malignant neoplasm of upper-outer quadrant of left male breast
C50.511Malignant neoplasm of lower-outer quadrant of right female breast
C50.512Malignant neoplasm of lower-outer quadrant of left female breast
C50.521Malignant neoplasm of lower-outer quadrant of right male breast
C50.522Malignant neoplasm of lower-outer quadrant of left male breast
C50.611Malignant neoplasm of axillary tail of right female breast
C50.612Malignant neoplasm of axillary tail of left female breast
C50.621Malignant neoplasm of axillary tail of right male breast
C50.622Malignant neoplasm of axillary tail of left male breast
C50.811Malignant neoplasm of overlapping sites of right female breast
C50.812Malignant neoplasm of overlapping sites of left female breast
C50.821Malignant neoplasm of overlapping sites of right male breast
C50.822Malignant neoplasm of overlapping sites of left male breast
C50.911Malignant neoplasm of unspecified site of right female breast
C50.912Malignant neoplasm of unspecified site of left female breast
C50.921Malignant neoplasm of unspecified site of right male breast
C50.922Malignant neoplasm of unspecified site of left male breast
C56.1Malignant neoplasm of right ovary
C56.2Malignant neoplasm of left ovary
C77.3Secondary and unspecified malignant neoplasm of axilla and upper limb lymph nodes
C78.01Secondary malignant neoplasm of right lung
C78.02Secondary malignant neoplasm of left lung
C78.1Secondary malignant neoplasm of mediastinum
C78.2Secondary malignant neoplasm of pleura
C78.7Secondary malignant neoplasm of liver and intrahepatic bile duct
C79.2Secondary malignant neoplasm of skin
C79.31Secondary malignant neoplasm of brain
C79.51Secondary malignant neoplasm of bone
C79.52Secondary malignant neoplasm of bone marrow
C79.81Secondary malignant neoplasm of breast
C80.0Disseminated malignant neoplasm, unspecified
C80.1Malignant (primary) neoplasm, unspecified
D04.5Carcinoma in situ of skin of trunk
D05.01Lobular carcinoma in situ of right breast
D05.02Lobular carcinoma in situ of left breast
D05.11Intraductal carcinoma in situ of right breast
D05.12Intraductal carcinoma in situ of left breast
D05.81Other specified type of carcinoma in situ of right breast
D05.82Other specified type of carcinoma in situ of left breast
D05.91Unspecified type of carcinoma in situ of right breast
D05.92Unspecified type of carcinoma in situ of left breast
D24.1Benign neoplasm of right breast
D24.2Benign neoplasm of left breast
D48.5Neoplasm of uncertain behavior of skin
D48.61Neoplasm of uncertain behavior of right breast
D48.62Neoplasm of uncertain behavior of left breast
D49.2Neoplasm of unspecified behavior of bone, soft tissue, and skin
D49.3Neoplasm of unspecified behavior of breast
I80.8Phlebitis and thrombophlebitis of other sites
N60.01Solitary cyst of right breast
N60.02Solitary cyst of left breast
N60.11Diffuse cystic mastopathy of right breast
N60.12Diffuse cystic mastopathy of left breast
N60.21Fibroadenosis of right breast
N60.22Fibroadenosis of left breast
N60.31Fibrosclerosis of right breast
N60.32Fibrosclerosis of left breast
N60.41Mammary duct ectasia of right breast
N60.42Mammary duct ectasia of left breast
N60.81Other benign mammary dysplasias of right breast
N60.82Other benign mammary dysplasias of left breast
N61.0Mastitis without abscess
N61.1Abscess of the breast and nipple
N61.21Granulomatous mastitis, right breast
N61.22Granulomatous mastitis, left breast
N61.23Granulomatous mastitis, bilateral breast
N62Hypertrophy of breast
N63.11Unspecified lump in the right breast, upper outer quadrant
N63.12Unspecified lump in the right breast, upper inner quadrant
N63.13Unspecified lump in the right breast, lower outer quadrant
N63.14Unspecified lump in the right breast, lower inner quadrant
N63.15Unspecified lump in the right breast, overlapping quadrants
N63.21Unspecified lump in the left breast, upper outer quadrant
N63.22Unspecified lump in the left breast, upper inner quadrant
N63.23Unspecified lump in the left breast, lower outer quadrant
N63.24Unspecified lump in the left breast, lower inner quadrant
N63.25Unspecified lump in the left breast, overlapping quadrants
N63.31Unspecified lump in axillary tail of the right breast
N63.32Unspecified lump in axillary tail of the left breast
N63.41Unspecified lump in right breast, subareolar
N63.42Unspecified lump in left breast, subareolar
N64.0Fissure and fistula of nipple
N64.1Fat necrosis of breast
N64.2Atrophy of breast
N64.3Galactorrhea not associated with childbirth
N64.4Mastodynia
N64.51Induration of breast
N64.52Nipple discharge
N64.53Retraction of nipple
N64.59Other signs and symptoms in breast
N64.89Other specified disorders of breast
N64.9Disorder of breast, unspecified
N65.0Deformity of reconstructed breast
N65.1Disproportion of reconstructed breast
R59.0Localized enlarged lymph nodes
R59.1Generalized enlarged lymph nodes
R59.9Enlarged lymph nodes, unspecified
R92.0Mammographic microcalcification found on diagnostic imaging of breast
R92.1Mammographic calcification found on diagnostic imaging of breast
R92.2Inconclusive mammogram
R92.8Other abnormal and inconclusive findings on diagnostic imaging of breast
S20.01XAContusion of right breast, initial encounter
S20.02XAContusion of left breast, initial encounter
S21.011ALaceration without foreign body of right breast, initial encounter
S21.012ALaceration without foreign body of left breast, initial encounter
S21.021ALaceration with foreign body of right breast, initial encounter
S21.022ALaceration with foreign body of left breast, initial encounter
S21.031APuncture wound without foreign body of right breast, initial encounter
S21.032APuncture wound without foreign body of left breast, initial encounter
S21.041APuncture wound with foreign body of right breast, initial encounter
S21.042APuncture wound with foreign body of left breast, initial encounter
S21.051AOpen bite of right breast, initial encounter
S21.052AOpen bite of left breast, initial encounter
S28.211AComplete traumatic amputation of right breast, initial encounter
S28.212AComplete traumatic amputation of left breast, initial encounter
S28.221APartial traumatic amputation of right breast, initial encounter
S28.222APartial traumatic amputation of left breast, initial encounter
T85.41XABreakdown (mechanical) of breast prosthesis and implant, initial encounter
T85.41XDBreakdown (mechanical) of breast prosthesis and implant, subsequent encounter
T85.41XSBreakdown (mechanical) of breast prosthesis and implant, sequela
T85.42XADisplacement of breast prosthesis and implant, initial encounter
T85.42XDDisplacement of breast prosthesis and implant, subsequent encounter
T85.42XSDisplacement of breast prosthesis and implant, sequela
T85.43XALeakage of breast prosthesis and implant, initial encounter
T85.43XDLeakage of breast prosthesis and implant, subsequent encounter
T85.43XSLeakage of breast prosthesis and implant, sequela
T85.44XACapsular contracture of breast implant, initial encounter
T85.44XDCapsular contracture of breast implant, subsequent encounter
T85.44XSCapsular contracture of breast implant, sequela
T85.49XAOther mechanical complication of breast prosthesis and implant, initial encounter
T85.49XDOther mechanical complication of breast prosthesis and implant, subsequent encounter
T85.49XSOther mechanical complication of breast prosthesis and implant, sequela
T85.79XAInfection and inflammatory reaction due to other internal prosthetic devices, implants and grafts, initial encounter
T85.79XDInfection and inflammatory reaction due to other internal prosthetic devices, implants and grafts, subsequent encounter
T85.79XSInfection and inflammatory reaction due to other internal prosthetic devices, implants and grafts, sequela
Z03.89Encounter for observation for other suspected diseases and conditions ruled out
Z08Encounter for follow-up examination after completed treatment for malignant neoplasm
Z09Encounter for follow-up examination after completed treatment for conditions other than malignant neoplasm
Z12.31Encounter for screening mammogram for malignant neoplasm of breast
Z77.118Contact with and (suspected) exposure to other environmental pollution
Z77.123Contact with and (suspected) exposure to radon and other naturally occurring radiation
Z77.128Contact with and (suspected) exposure to other hazards in the physical environment
Z77.22Contact with and (suspected) exposure to environmental tobacco smoke (acute) (chronic)
Z77.9Other contact with and (suspected) exposures hazardous to health
Z85.3Personal history of malignant neoplasm of breast
Z85.831Personal history of malignant neoplasm of soft tissue
Z85.89Personal history of malignant neoplasm of other organs and systems
Z86.000Personal history of in-situ neoplasm of breast
Z86.018Personal history of other benign neoplasm
Z86.03Personal history of neoplasm of uncertain behavior
Z87.42Personal history of other diseases of the female genital tract
Z92.89Personal history of other medical treatment
Z98.86Personal history of breast implant removal

Frequently asked questions

Which ICD-10 codes support medical necessity for CPT 76641?

Medicare coverage policies (LCDs/NCDs and Billing & Coding articles) list 173 ICD-10 diagnosis codes that support medical necessity for CPT 76641. The covered codes are listed on this page. Coverage varies by MAC/state — always confirm against the policy that applies to you.

What is a medical-necessity (LCD/NCD) crosswalk?

A claim whose procedure isn't supported by a covered diagnosis denies as "not medically necessary" (CARC 50). CMS coverage policies define which diagnoses justify a procedure; this page is the ICD-10 → CPT 76641 view of that relationship.

Catch medical-necessity denials before you bill. CareNiva scrubs claims against LCD/NCD coverage and flags unsupported diagnoses — in the same platform you run visits and billing.

More free billing tools: all crosswalks · NCCI edits · Medicare fees · denial codes

Informational only, not coding, billing, or legal advice. Based on CMS Medicare Coverage Database data; verify the current LCD/NCD for your MAC before billing.

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