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ICD↔CPT crosswalk

CPT 45379: ICD-10 codes that support medical necessity

712 covered diagnosis codes under Medicare coverage policies (LCD/NCD)

These ICD-10-CM diagnoses support medical necessity for CPT 45379 under Medicare coverage policies (LCDs, NCDs, and Billing & Coding articles). Billing CPT 45379 with a diagnosis that isn't covered typically denies as CARC 50 — not medically necessary.

National approximation. Coverage varies by MAC and state — confirm against the specific LCD/NCD and article that applies to your jurisdiction and date of service.

ICD-10Description
A03.9Shigellosis, unspecified
A04.3Enterohemorrhagic Escherichia coli infection
A04.5Campylobacter enteritis
A04.6Enteritis due to Yersinia enterocolitica
A04.71Enterocolitis due to Clostridium difficile, recurrent
A04.72Enterocolitis due to Clostridium difficile, not specified as recurrent
A04.8Other specified bacterial intestinal infections
A04.9Bacterial intestinal infection, unspecified
A06.0Acute amebic dysentery
A06.1Chronic intestinal amebiasis
A06.2Amebic nondysenteric colitis
A06.9Amebiasis, unspecified
A07.0Balantidiasis
A07.3Isosporiasis
A07.8Other specified protozoal intestinal diseases
A08.0Rotaviral enteritis
A08.11Acute gastroenteropathy due to Norwalk agent
A08.19Acute gastroenteropathy due to other small round viruses
A08.2Adenoviral enteritis
A08.31Calicivirus enteritis
A08.32Astrovirus enteritis
A08.39Other viral enteritis
A09Infectious gastroenteritis and colitis, unspecified
A18.31Tuberculous peritonitis
A18.32Tuberculous enteritis
A18.39Retroperitoneal tuberculosis
A18.83Tuberculosis of digestive tract organs, not elsewhere classified
A41.01Sepsis due to Methicillin susceptible Staphylococcus aureus
A41.02Sepsis due to Methicillin resistant Staphylococcus aureus
A41.4Sepsis due to anaerobes
A41.50Gram-negative sepsis, unspecified
A41.51Sepsis due to Escherichia coli [E. coli]
A41.52Sepsis due to Pseudomonas
A41.53Sepsis due to Serratia
A41.54Sepsis due to Acinetobacter baumannii
A41.59Other Gram-negative sepsis
A41.81Sepsis due to Enterococcus
A41.89Other specified sepsis
A42.7Actinomycotic sepsis
A54.6Gonococcal infection of anus and rectum
A55Chlamydial lymphogranuloma (venereum)
B20Human immunodeficiency virus [HIV] disease
B37.82Candidal enteritis
B65.1Schistosomiasis due to Schistosoma mansoni [intestinal schistosomiasis]
B68.0Taenia solium taeniasis
B68.1Taenia saginata taeniasis
B68.9Taeniasis, unspecified
B70.0Diphyllobothriasis
B71.0Hymenolepiasis
B71.1Dipylidiasis
B71.8Other specified cestode infections
B76.8Other hookworm diseases
B76.9Hookworm disease, unspecified
B77.0Ascariasis with intestinal complications
B77.81Ascariasis pneumonia
B77.89Ascariasis with other complications
B77.9Ascariasis, unspecified
B78.0Intestinal strongyloidiasis
B78.7Disseminated strongyloidiasis
B78.9Strongyloidiasis, unspecified
B79Trichuriasis
B80Enterobiasis
B82.0Intestinal helminthiasis, unspecified
B82.9Intestinal parasitism, unspecified
B83.9Helminthiasis, unspecified
B95.1Streptococcus, group B, as the cause of diseases classified elsewhere
B95.2Enterococcus as the cause of diseases classified elsewhere
C17.2Malignant neoplasm of ileum
C18.0Malignant neoplasm of cecum
C18.1Malignant neoplasm of appendix
C18.2Malignant neoplasm of ascending colon
C18.3Malignant neoplasm of hepatic flexure
C18.4Malignant neoplasm of transverse colon
C18.5Malignant neoplasm of splenic flexure
C18.6Malignant neoplasm of descending colon
C18.7Malignant neoplasm of sigmoid colon
C18.8Malignant neoplasm of overlapping sites of colon
C18.9Malignant neoplasm of colon, unspecified
C19Malignant neoplasm of rectosigmoid junction
C20Malignant neoplasm of rectum
C21.0Malignant neoplasm of anus, unspecified
C21.1Malignant neoplasm of anal canal
C21.2Malignant neoplasm of cloacogenic zone
C21.8Malignant neoplasm of overlapping sites of rectum, anus and anal canal
C26.0Malignant neoplasm of intestinal tract, part unspecified
C26.9Malignant neoplasm of ill-defined sites within the digestive system
C45.1Mesothelioma of peritoneum
C46.4Kaposi's sarcoma of gastrointestinal sites
C48.1Malignant neoplasm of specified parts of peritoneum
C48.2Malignant neoplasm of peritoneum, unspecified
C48.8Malignant neoplasm of overlapping sites of retroperitoneum and peritoneum
C49.4Malignant neoplasm of connective and soft tissue of abdomen
C49.A3Gastrointestinal stromal tumor of small intestine
C49.A4Gastrointestinal stromal tumor of large intestine
C49.A5Gastrointestinal stromal tumor of rectum
C49.A9Gastrointestinal stromal tumor of other sites
C76.2Malignant neoplasm of abdomen
C76.3Malignant neoplasm of pelvis
C77.2Secondary and unspecified malignant neoplasm of intra-abdominal lymph nodes
C78.4Secondary malignant neoplasm of small intestine
C78.5Secondary malignant neoplasm of large intestine and rectum
C78.6Secondary malignant neoplasm of retroperitoneum and peritoneum
C78.7Secondary malignant neoplasm of liver and intrahepatic bile duct
C7A.00Malignant carcinoid tumor of unspecified site
C7A.010Malignant carcinoid tumor of the duodenum
C7A.011Malignant carcinoid tumor of the jejunum
C7A.012Malignant carcinoid tumor of the ileum
C7A.019Malignant carcinoid tumor of the small intestine, unspecified portion
C7A.020Malignant carcinoid tumor of the appendix
C7A.021Malignant carcinoid tumor of the cecum
C7A.022Malignant carcinoid tumor of the ascending colon
C7A.023Malignant carcinoid tumor of the transverse colon
C7A.024Malignant carcinoid tumor of the descending colon
C7A.025Malignant carcinoid tumor of the sigmoid colon
C7A.026Malignant carcinoid tumor of the rectum
C7A.029Malignant carcinoid tumor of the large intestine, unspecified portion
C7A.096Malignant carcinoid tumor of the hindgut, unspecified
C7A.098Malignant carcinoid tumors of other sites
C7A.1Malignant poorly differentiated neuroendocrine tumors
C7A.8Other malignant neuroendocrine tumors
C7B.04Secondary carcinoid tumors of peritoneum
C7B.09Secondary carcinoid tumors of other sites
C7B.1Secondary Merkel cell carcinoma
C7B.8Other secondary neuroendocrine tumors
C80.0Disseminated malignant neoplasm, unspecified
C80.2Malignant neoplasm associated with transplanted organ
C82.09Follicular lymphoma grade I, extranodal and solid organ sites
C82.19Follicular lymphoma grade II, extranodal and solid organ sites
C82.29Follicular lymphoma grade III, unspecified, extranodal and solid organ sites
C82.39Follicular lymphoma grade IIIa, extranodal and solid organ sites
C82.49Follicular lymphoma grade IIIb, extranodal and solid organ sites
C82.89Other types of follicular lymphoma, extranodal and solid organ sites
C82.99Follicular lymphoma, unspecified, extranodal and solid organ sites
C83.398Diffuse large B-cell lymphoma of other extranodal and solid organ sites
C88.40Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma] not having achieved remission
D00.1Carcinoma in situ of esophagus
D00.2Carcinoma in situ of stomach
D01.0Carcinoma in situ of colon
D01.1Carcinoma in situ of rectosigmoid junction
D01.2Carcinoma in situ of rectum
D01.3Carcinoma in situ of anus and anal canal
D12.0Benign neoplasm of cecum
D12.1Benign neoplasm of appendix
D12.2Benign neoplasm of ascending colon
D12.3Benign neoplasm of transverse colon
D12.4Benign neoplasm of descending colon
D12.5Benign neoplasm of sigmoid colon
D12.6Benign neoplasm of colon, unspecified
D12.7Benign neoplasm of rectosigmoid junction
D12.8Benign neoplasm of rectum
D12.9Benign neoplasm of anus and anal canal
D13.91Familial adenomatous polyposis
D17.5Benign lipomatous neoplasm of intra-abdominal organs
D17.71Benign lipomatous neoplasm of kidney
D17.79Benign lipomatous neoplasm of other sites
D18.03Hemangioma of intra-abdominal structures
D18.1Lymphangioma, any site
D37.1Neoplasm of uncertain behavior of stomach
D37.2Neoplasm of uncertain behavior of small intestine
D37.3Neoplasm of uncertain behavior of appendix
D37.4Neoplasm of uncertain behavior of colon
D37.5Neoplasm of uncertain behavior of rectum
D37.8Neoplasm of uncertain behavior of other specified digestive organs
D37.9Neoplasm of uncertain behavior of digestive organ, unspecified
D3A.00Benign carcinoid tumor of unspecified site
D3A.010Benign carcinoid tumor of the duodenum
D3A.011Benign carcinoid tumor of the jejunum
D3A.012Benign carcinoid tumor of the ileum
D3A.019Benign carcinoid tumor of the small intestine, unspecified portion
D3A.020Benign carcinoid tumor of the appendix
D3A.021Benign carcinoid tumor of the cecum
D3A.022Benign carcinoid tumor of the ascending colon
D3A.023Benign carcinoid tumor of the transverse colon
D3A.024Benign carcinoid tumor of the descending colon
D3A.025Benign carcinoid tumor of the sigmoid colon
D3A.026Benign carcinoid tumor of the rectum
D3A.029Benign carcinoid tumor of the large intestine, unspecified portion
D3A.096Benign carcinoid tumor of the hindgut, unspecified
D3A.8Other benign neuroendocrine tumors
D49.0Neoplasm of unspecified behavior of digestive system
D50.0Iron deficiency anemia secondary to blood loss (chronic)
D50.9Iron deficiency anemia, unspecified
D62Acute posthemorrhagic anemia
E34.00Carcinoid syndrome, unspecified
E34.01Carcinoid heart syndrome
E34.09Other carcinoid syndrome
E44.0Moderate protein-calorie malnutrition
I33.0Acute and subacute infective endocarditis
I77.2Rupture of artery
I78.0Hereditary hemorrhagic telangiectasia
I86.4Gastric varices
K35.80Unspecified acute appendicitis
K35.890Other acute appendicitis without perforation or gangrene
K35.891Other acute appendicitis without perforation, with gangrene
K38.0Hyperplasia of appendix
K38.1Appendicular concretions
K38.2Diverticulum of appendix
K38.3Fistula of appendix
K38.8Other specified diseases of appendix
K38.9Disease of appendix, unspecified
K50.00Crohn's disease of small intestine without complications
K50.011Crohn's disease of small intestine with rectal bleeding
K50.012Crohn's disease of small intestine with intestinal obstruction
K50.013Crohn's disease of small intestine with fistula
K50.014Crohn's disease of small intestine with abscess
K50.018Crohn's disease of small intestine with other complication
K50.019Crohn's disease of small intestine with unspecified complications
K50.10Crohn's disease of large intestine without complications
K50.111Crohn's disease of large intestine with rectal bleeding
K50.112Crohn's disease of large intestine with intestinal obstruction
K50.113Crohn's disease of large intestine with fistula
K50.114Crohn's disease of large intestine with abscess
K50.118Crohn's disease of large intestine with other complication
K50.119Crohn's disease of large intestine with unspecified complications
K50.80Crohn's disease of both small and large intestine without complications
K50.811Crohn's disease of both small and large intestine with rectal bleeding
K50.812Crohn's disease of both small and large intestine with intestinal obstruction
K50.813Crohn's disease of both small and large intestine with fistula
K50.814Crohn's disease of both small and large intestine with abscess
K50.818Crohn's disease of both small and large intestine with other complication
K50.819Crohn's disease of both small and large intestine with unspecified complications
K50.90Crohn's disease, unspecified, without complications
K50.911Crohn's disease, unspecified, with rectal bleeding
K50.912Crohn's disease, unspecified, with intestinal obstruction
K50.913Crohn's disease, unspecified, with fistula
K50.914Crohn's disease, unspecified, with abscess
K50.918Crohn's disease, unspecified, with other complication
K50.919Crohn's disease, unspecified, with unspecified complications
K51.00Ulcerative (chronic) pancolitis without complications
K51.011Ulcerative (chronic) pancolitis with rectal bleeding
K51.012Ulcerative (chronic) pancolitis with intestinal obstruction
K51.013Ulcerative (chronic) pancolitis with fistula
K51.014Ulcerative (chronic) pancolitis with abscess
K51.018Ulcerative (chronic) pancolitis with other complication
K51.019Ulcerative (chronic) pancolitis with unspecified complications
K51.20Ulcerative (chronic) proctitis without complications
K51.211Ulcerative (chronic) proctitis with rectal bleeding
K51.212Ulcerative (chronic) proctitis with intestinal obstruction
K51.213Ulcerative (chronic) proctitis with fistula
K51.214Ulcerative (chronic) proctitis with abscess
K51.218Ulcerative (chronic) proctitis with other complication
K51.219Ulcerative (chronic) proctitis with unspecified complications
K51.30Ulcerative (chronic) rectosigmoiditis without complications
K51.311Ulcerative (chronic) rectosigmoiditis with rectal bleeding
K51.312Ulcerative (chronic) rectosigmoiditis with intestinal obstruction
K51.313Ulcerative (chronic) rectosigmoiditis with fistula
K51.314Ulcerative (chronic) rectosigmoiditis with abscess
K51.318Ulcerative (chronic) rectosigmoiditis with other complication
K51.319Ulcerative (chronic) rectosigmoiditis with unspecified complications
K51.40Inflammatory polyps of colon without complications
K51.411Inflammatory polyps of colon with rectal bleeding
K51.412Inflammatory polyps of colon with intestinal obstruction
K51.413Inflammatory polyps of colon with fistula
K51.414Inflammatory polyps of colon with abscess
K51.418Inflammatory polyps of colon with other complication
K51.419Inflammatory polyps of colon with unspecified complications
K51.50Left sided colitis without complications
K51.511Left sided colitis with rectal bleeding
K51.512Left sided colitis with intestinal obstruction
K51.513Left sided colitis with fistula
K51.514Left sided colitis with abscess
K51.518Left sided colitis with other complication
K51.519Left sided colitis with unspecified complications
K51.80Other ulcerative colitis without complications
K51.811Other ulcerative colitis with rectal bleeding
K51.812Other ulcerative colitis with intestinal obstruction
K51.813Other ulcerative colitis with fistula
K51.814Other ulcerative colitis with abscess
K51.818Other ulcerative colitis with other complication
K51.819Other ulcerative colitis with unspecified complications
K51.90Ulcerative colitis, unspecified, without complications
K51.911Ulcerative colitis, unspecified with rectal bleeding
K51.912Ulcerative colitis, unspecified with intestinal obstruction
K51.913Ulcerative colitis, unspecified with fistula
K51.914Ulcerative colitis, unspecified with abscess
K51.918Ulcerative colitis, unspecified with other complication
K51.919Ulcerative colitis, unspecified with unspecified complications
K52.0Gastroenteritis and colitis due to radiation
K52.1Toxic gastroenteritis and colitis
K52.21Food protein-induced enterocolitis syndrome
K52.22Food protein-induced enteropathy
K52.29Other allergic and dietetic gastroenteritis and colitis
K52.3Indeterminate colitis
K52.81Eosinophilic gastritis or gastroenteritis
K52.82Eosinophilic colitis
K52.831Collagenous colitis
K52.832Lymphocytic colitis
K52.838Other microscopic colitis
K52.839Microscopic colitis, unspecified
K52.89Other specified noninfective gastroenteritis and colitis
K52.9Noninfective gastroenteritis and colitis, unspecified
K55.011Focal (segmental) acute (reversible) ischemia of small intestine
K55.012Diffuse acute (reversible) ischemia of small intestine
K55.019Acute (reversible) ischemia of small intestine, extent unspecified
K55.021Focal (segmental) acute infarction of small intestine
K55.022Diffuse acute infarction of small intestine
K55.029Acute infarction of small intestine, extent unspecified
K55.031Focal (segmental) acute (reversible) ischemia of large intestine
K55.032Diffuse acute (reversible) ischemia of large intestine
K55.039Acute (reversible) ischemia of large intestine, extent unspecified
K55.041Focal (segmental) acute infarction of large intestine
K55.042Diffuse acute infarction of large intestine
K55.049Acute infarction of large intestine, extent unspecified
K55.051Focal (segmental) acute (reversible) ischemia of intestine, part unspecified
K55.052Diffuse acute (reversible) ischemia of intestine, part unspecified
K55.059Acute (reversible) ischemia of intestine, part and extent unspecified
K55.061Focal (segmental) acute infarction of intestine, part unspecified
K55.062Diffuse acute infarction of intestine, part unspecified
K55.069Acute infarction of intestine, part and extent unspecified
K55.1Chronic vascular disorders of intestine
K55.20Angiodysplasia of colon without hemorrhage
K55.21Angiodysplasia of colon with hemorrhage
K55.30Necrotizing enterocolitis, unspecified
K55.31Stage 1 necrotizing enterocolitis
K55.32Stage 2 necrotizing enterocolitis
K55.33Stage 3 necrotizing enterocolitis
K55.8Other vascular disorders of intestine
K55.9Vascular disorder of intestine, unspecified
K56.0Paralytic ileus
K56.1Intussusception
K56.2Volvulus
K56.3Gallstone ileus
K56.41Fecal impaction
K56.49Other impaction of intestine
K56.50Intestinal adhesions [bands], unspecified as to partial versus complete obstruction
K56.51Intestinal adhesions [bands], with partial obstruction
K56.52Intestinal adhesions [bands] with complete obstruction
K56.600Partial intestinal obstruction, unspecified as to cause
K56.601Complete intestinal obstruction, unspecified as to cause
K56.609Unspecified intestinal obstruction, unspecified as to partial versus complete obstruction
K56.690Other partial intestinal obstruction
K56.691Other complete intestinal obstruction
K56.699Other intestinal obstruction unspecified as to partial versus complete obstruction
K56.7Ileus, unspecified
K57.00Diverticulitis of small intestine with perforation and abscess without bleeding
K57.01Diverticulitis of small intestine with perforation and abscess with bleeding
K57.10Diverticulosis of small intestine without perforation or abscess without bleeding
K57.11Diverticulosis of small intestine without perforation or abscess with bleeding
K57.20Diverticulitis of large intestine with perforation and abscess without bleeding
K57.21Diverticulitis of large intestine with perforation and abscess with bleeding
K57.30Diverticulosis of large intestine without perforation or abscess without bleeding
K57.31Diverticulosis of large intestine without perforation or abscess with bleeding
K57.32Diverticulitis of large intestine without perforation or abscess without bleeding
K57.33Diverticulitis of large intestine without perforation or abscess with bleeding
K57.40Diverticulitis of both small and large intestine with perforation and abscess without bleeding
K57.41Diverticulitis of both small and large intestine with perforation and abscess with bleeding
K57.50Diverticulosis of both small and large intestine without perforation or abscess without bleeding
K57.51Diverticulosis of both small and large intestine without perforation or abscess with bleeding
K57.52Diverticulitis of both small and large intestine without perforation or abscess without bleeding
K57.53Diverticulitis of both small and large intestine without perforation or abscess with bleeding
K57.80Diverticulitis of intestine, part unspecified, with perforation and abscess without bleeding
K57.81Diverticulitis of intestine, part unspecified, with perforation and abscess with bleeding
K57.90Diverticulosis of intestine, part unspecified, without perforation or abscess without bleeding
K57.91Diverticulosis of intestine, part unspecified, without perforation or abscess with bleeding
K57.92Diverticulitis of intestine, part unspecified, without perforation or abscess without bleeding
K57.93Diverticulitis of intestine, part unspecified, without perforation or abscess with bleeding
K58.0Irritable bowel syndrome with diarrhea
K58.1Irritable bowel syndrome with constipation
K58.2Mixed irritable bowel syndrome
K58.8Other irritable bowel syndrome
K58.9Irritable bowel syndrome, unspecified
K59.00Constipation, unspecified
K59.01Slow transit constipation
K59.02Outlet dysfunction constipation
K59.03Drug induced constipation
K59.04Chronic idiopathic constipation
K59.09Other constipation
K59.1Functional diarrhea
K59.2Neurogenic bowel, not elsewhere classified
K59.31Toxic megacolon
K59.39Other megacolon
K59.4Anal spasm
K59.81Ogilvie syndrome
K59.89Other specified functional intestinal disorders
K60.30Anal fistula, unspecified
K60.311Anal fistula, simple, initial
K60.312Anal fistula, simple, persistent
K60.313Anal fistula, simple, recurrent
K60.319Anal fistula, simple, unspecified
K60.321Anal fistula, complex, initial
K60.322Anal fistula, complex, persistent
K60.323Anal fistula, complex, recurrent
K60.329Anal fistula, complex, unspecified
K60.40Rectal fistula, unspecified
K60.411Rectal fistula, simple, initial
K60.412Rectal fistula, simple, persistent
K60.413Rectal fistula, simple, recurrent
K60.419Rectal fistula, simple, unspecified
K60.421Rectal fistula, complex, initial
K60.422Rectal fistula, complex, persistent
K60.423Rectal fistula, complex, recurrent
K60.429Rectal fistula, complex, unspecified
K60.50Anorectal fistula, unspecified
K60.511Anorectal fistula, simple, initial
K60.512Anorectal fistula, simple, persistent
K60.513Anorectal fistula, simple, recurrent
K60.519Anorectal fistula, simple, unspecified
K60.521Anorectal fistula, complex, initial
K60.522Anorectal fistula, complex, persistent
K60.523Anorectal fistula, complex, recurrent

Showing the first 400 of 712 covered codes — this procedure has a large covered-diagnosis set; see the governing LCD/article for the complete list.

Frequently asked questions

Which ICD-10 codes support medical necessity for CPT 45379?

Medicare coverage policies (LCDs/NCDs and Billing & Coding articles) list 712 ICD-10 diagnosis codes that support medical necessity for CPT 45379. The covered codes are listed on this page. Coverage varies by MAC/state — always confirm against the policy that applies to you.

What is a medical-necessity (LCD/NCD) crosswalk?

A claim whose procedure isn't supported by a covered diagnosis denies as "not medically necessary" (CARC 50). CMS coverage policies define which diagnoses justify a procedure; this page is the ICD-10 → CPT 45379 view of that relationship.

Catch medical-necessity denials before you bill. CareNiva scrubs claims against LCD/NCD coverage and flags unsupported diagnoses — in the same platform you run visits and billing.

More free billing tools: all crosswalks · NCCI edits · Medicare fees · denial codes

Informational only, not coding, billing, or legal advice. Based on CMS Medicare Coverage Database data; verify the current LCD/NCD for your MAC before billing.

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