ICD↔CPT crosswalk
CPT 22510: ICD-10 codes that support medical necessity
These ICD-10-CM diagnoses support medical necessity for CPT 22510 under Medicare coverage policies (LCDs, NCDs, and Billing & Coding articles). Billing CPT 22510 with a diagnosis that isn't covered typically denies as CARC 50 — not medically necessary.
National approximation. Coverage varies by MAC and state — confirm against the specific LCD/NCD and article that applies to your jurisdiction and date of service.
| ICD-10 | Description |
|---|---|
| C41.2 | Malignant neoplasm of vertebral column |
| C79.51 | Secondary malignant neoplasm of bone |
| C79.52 | Secondary malignant neoplasm of bone marrow |
| C90.00 | Multiple myeloma not having achieved remission |
| C90.01 | Multiple myeloma in remission |
| C90.02 | Multiple myeloma in relapse |
| C96.5 | Multifocal and unisystemic Langerhans-cell histiocytosis |
| C96.6 | Unifocal Langerhans-cell histiocytosis |
| C96.A | Histiocytic sarcoma |
| D16.6 | Benign neoplasm of vertebral column |
| D47.1 | Chronic myeloproliferative disease |
| E24.0 | Pituitary-dependent Cushing's disease |
| E24.1 | Nelson's syndrome |
| E24.2 | Drug-induced Cushing's syndrome |
| E24.3 | Ectopic ACTH syndrome |
| E24.4 | Alcohol-induced pseudo-Cushing's syndrome |
| E24.8 | Other Cushing's syndrome |
| E24.9 | Cushing's syndrome, unspecified |
| M48.33 | Traumatic spondylopathy, cervicothoracic region |
| M48.34 | Traumatic spondylopathy, thoracic region |
| M48.35 | Traumatic spondylopathy, thoracolumbar region |
| M48.36 | Traumatic spondylopathy, lumbar region |
| M48.37 | Traumatic spondylopathy, lumbosacral region |
| M80.08XA | Age-related osteoporosis with current pathological fracture, vertebra(e), initial encounter for fracture |
| M80.08XG | Age-related osteoporosis with current pathological fracture, vertebra(e), subsequent encounter for fracture with delayed healing |
| M80.08XK | Age-related osteoporosis with current pathological fracture, vertebra(e), subsequent encounter for fracture with nonunion |
| M80.08XP | Age-related osteoporosis with current pathological fracture, vertebra(e), subsequent encounter for fracture with malunion |
| M80.08XS | Age-related osteoporosis with current pathological fracture, vertebra(e), sequela |
| M80.88XA | Other osteoporosis with current pathological fracture, vertebra(e), initial encounter for fracture |
| M80.88XS | Other osteoporosis with current pathological fracture, vertebra(e), sequela |
| M81.6 | Localized osteoporosis [Lequesne] |
| M84.58XA | Pathological fracture in neoplastic disease, other specified site, initial encounter for fracture |
| M84.58XD | Pathological fracture in neoplastic disease, other specified site, subsequent encounter for fracture with routine healing |
| M84.58XG | Pathological fracture in neoplastic disease, other specified site, subsequent encounter for fracture with delayed healing |
| M84.58XK | Pathological fracture in neoplastic disease, other specified site, subsequent encounter for fracture with nonunion |
| M84.58XP | Pathological fracture in neoplastic disease, other specified site, subsequent encounter for fracture with malunion |
| M84.58XS | Pathological fracture in neoplastic disease, other specified site, sequela |
| S12.690A | Other displaced fracture of seventh cervical vertebra, initial encounter for closed fracture |
| S12.691A | Other nondisplaced fracture of seventh cervical vertebra, initial encounter for closed fracture |
| S22.010A | Wedge compression fracture of first thoracic vertebra, initial encounter for closed fracture |
| S22.011A | Stable burst fracture of first thoracic vertebra, initial encounter for closed fracture |
| S22.012A | Unstable burst fracture of first thoracic vertebra, initial encounter for closed fracture |
| S22.018A | Other fracture of first thoracic vertebra, initial encounter for closed fracture |
| S22.020A | Wedge compression fracture of second thoracic vertebra, initial encounter for closed fracture |
| S22.021A | Stable burst fracture of second thoracic vertebra, initial encounter for closed fracture |
| S22.022A | Unstable burst fracture of second thoracic vertebra, initial encounter for closed fracture |
| S22.028A | Other fracture of second thoracic vertebra, initial encounter for closed fracture |
| S22.030A | Wedge compression fracture of third thoracic vertebra, initial encounter for closed fracture |
| S22.031A | Stable burst fracture of third thoracic vertebra, initial encounter for closed fracture |
| S22.032A | Unstable burst fracture of third thoracic vertebra, initial encounter for closed fracture |
| S22.038A | Other fracture of third thoracic vertebra, initial encounter for closed fracture |
| S22.040A | Wedge compression fracture of fourth thoracic vertebra, initial encounter for closed fracture |
| S22.041A | Stable burst fracture of fourth thoracic vertebra, initial encounter for closed fracture |
| S22.042A | Unstable burst fracture of fourth thoracic vertebra, initial encounter for closed fracture |
| S22.048A | Other fracture of fourth thoracic vertebra, initial encounter for closed fracture |
| S22.050A | Wedge compression fracture of T5-T6 vertebra, initial encounter for closed fracture |
| S22.051A | Stable burst fracture of T5-T6 vertebra, initial encounter for closed fracture |
| S22.052A | Unstable burst fracture of T5-T6 vertebra, initial encounter for closed fracture |
| S22.058A | Other fracture of T5-T6 vertebra, initial encounter for closed fracture |
| S22.060A | Wedge compression fracture of T7-T8 vertebra, initial encounter for closed fracture |
| S22.061A | Stable burst fracture of T7-T8 vertebra, initial encounter for closed fracture |
| S22.062A | Unstable burst fracture of T7-T8 vertebra, initial encounter for closed fracture |
| S22.068A | Other fracture of T7-T8 thoracic vertebra, initial encounter for closed fracture |
| S22.070A | Wedge compression fracture of T9-T10 vertebra, initial encounter for closed fracture |
| S22.071A | Stable burst fracture of T9-T10 vertebra, initial encounter for closed fracture |
| S22.072A | Unstable burst fracture of T9-T10 vertebra, initial encounter for closed fracture |
| S22.078A | Other fracture of T9-T10 vertebra, initial encounter for closed fracture |
| S22.080A | Wedge compression fracture of T11-T12 vertebra, initial encounter for closed fracture |
| S22.081A | Stable burst fracture of T11-T12 vertebra, initial encounter for closed fracture |
| S22.082A | Unstable burst fracture of T11-T12 vertebra, initial encounter for closed fracture |
| S22.088A | Other fracture of T11-T12 vertebra, initial encounter for closed fracture |
| S32.010A | Wedge compression fracture of first lumbar vertebra, initial encounter for closed fracture |
| S32.011A | Stable burst fracture of first lumbar vertebra, initial encounter for closed fracture |
| S32.012A | Unstable burst fracture of first lumbar vertebra, initial encounter for closed fracture |
| S32.018A | Other fracture of first lumbar vertebra, initial encounter for closed fracture |
| S32.020A | Wedge compression fracture of second lumbar vertebra, initial encounter for closed fracture |
| S32.021A | Stable burst fracture of second lumbar vertebra, initial encounter for closed fracture |
| S32.022A | Unstable burst fracture of second lumbar vertebra, initial encounter for closed fracture |
| S32.028A | Other fracture of second lumbar vertebra, initial encounter for closed fracture |
| S32.030A | Wedge compression fracture of third lumbar vertebra, initial encounter for closed fracture |
| S32.031A | Stable burst fracture of third lumbar vertebra, initial encounter for closed fracture |
| S32.032A | Unstable burst fracture of third lumbar vertebra, initial encounter for closed fracture |
| S32.038A | Other fracture of third lumbar vertebra, initial encounter for closed fracture |
| S32.040A | Wedge compression fracture of fourth lumbar vertebra, initial encounter for closed fracture |
| S32.041A | Stable burst fracture of fourth lumbar vertebra, initial encounter for closed fracture |
| S32.042A | Unstable burst fracture of fourth lumbar vertebra, initial encounter for closed fracture |
| S32.048A | Other fracture of fourth lumbar vertebra, initial encounter for closed fracture |
| S32.050A | Wedge compression fracture of fifth lumbar vertebra, initial encounter for closed fracture |
| S32.051A | Stable burst fracture of fifth lumbar vertebra, initial encounter for closed fracture |
| S32.052A | Unstable burst fracture of fifth lumbar vertebra, initial encounter for closed fracture |
| S32.058A | Other fracture of fifth lumbar vertebra, initial encounter for closed fracture |
| T38.0X5A | Adverse effect of glucocorticoids and synthetic analogues, initial encounter |
| T38.0X5D | Adverse effect of glucocorticoids and synthetic analogues, subsequent encounter |
| T38.0X5S | Adverse effect of glucocorticoids and synthetic analogues, sequela |
Frequently asked questions
Which ICD-10 codes support medical necessity for CPT 22510?
Medicare coverage policies (LCDs/NCDs and Billing & Coding articles) list 94 ICD-10 diagnosis codes that support medical necessity for CPT 22510. The covered codes are listed on this page. Coverage varies by MAC/state — always confirm against the policy that applies to you.
What is a medical-necessity (LCD/NCD) crosswalk?
A claim whose procedure isn't supported by a covered diagnosis denies as "not medically necessary" (CARC 50). CMS coverage policies define which diagnoses justify a procedure; this page is the ICD-10 → CPT 22510 view of that relationship.
Catch medical-necessity denials before you bill. CareNiva scrubs claims against LCD/NCD coverage and flags unsupported diagnoses — in the same platform you run visits and billing.
More free billing tools: all crosswalks · NCCI edits · Medicare fees · denial codes
Informational only, not coding, billing, or legal advice. Based on CMS Medicare Coverage Database data; verify the current LCD/NCD for your MAC before billing.
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