E88: Other and unspecified metabolic disorders

Codes under E88 (Other and unspecified metabolic disorders). A ✓ marks a billable (fully specified) code; category codes without a ✓ are not billable on their own.

Code	Description	Billable
E88.0	Disorders of plasma-protein metabolism, not elsewhere classified	—
E88.01	Alpha-1-antitrypsin deficiency	✓
E88.1	Lipodystrophy, not elsewhere classified	—
E88.02	Plasminogen deficiency	✓
E88.2	Lipomatosis, not elsewhere classified	✓
E88.3	Tumor lysis syndrome	✓
E88.4	Mitochondrial metabolism disorders	—
E88.8	Other specified metabolic disorders	—
E88.09	Other disorders of plasma-protein metabolism, not elsewhere classified	✓
E88.9	Metabolic disorder, unspecified	✓
E88.10	Lipodystrophy, unspecified	✓
E88.11	Partial lipodystrophy	✓
E88.12	Generalized lipodystrophy	✓
E88.13	Localized lipodystrophy	✓
E88.14	HIV-associated lipodystrophy	✓
E88.19	Other lipodystrophy, not elsewhere classified	✓
E88.40	Mitochondrial metabolism disorder, unspecified	✓
E88.41	MELAS syndrome	✓
E88.42	MERRF syndrome	✓
E88.43	Disorders of mitochondrial tRNA synthetases	✓
E88.49	Other mitochondrial metabolism disorders	✓
E88.81	Metabolic syndrome and other insulin resistance	—
E88.82	Obesity due to disruption of MC4R pathway	✓
E88.89	Other specified metabolic disorders	✓
E88.810	Metabolic syndrome	✓
E88.811	Insulin resistance syndrome, Type A	✓
E88.818	Other insulin resistance	✓
E88.819	Insulin resistance, unspecified	✓
E88.A	Wasting disease (syndrome) due to underlying condition	✓

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Informational only, not coding or medical advice. Verify against the official ICD-10-CM (FY2026) and your payer's guidelines.

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